Several components of the GH axis are involved in tumor progression, and GH-induced
intracellular signaling has been strongly associated with breast cancer susceptibility in …

Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no
irradiation to the surrounding normal tissue and organs, results in maximum tumor control …

Background Approximately half of all patients with tumors need radiotherapy. Long-term
survivors may suffer from late sequelae of the treatment. The existing radiotherapeutic …

Background Central nervous system tumors are now the most common primary neoplasms
seen in children, and radiation therapy is a key component in management. Secondary …

Background The aim of our study is to determine the incidence, timing, and risk factors for
cerebral vasculopathy after cranial proton and photon radiation for pediatric brain tumors …

BACKGROUND Both intensity‐modulated radiotherapy (RT) and passively scattered proton
therapy have a risk of secondary malignant neoplasm (SMN) in children. To determine the …

Embryonal tumors (ET) of the central nervous system (CNS) in children encompass a wide
clinical spectrum of aggressive malignancies. Until recently, the overlapping morphological …

Radiotherapy is an essential element in the multidisciplinary management of children with
medulloblastoma and postoperative craniospinal axis radiotherapy is considered to be the …

Background Survivors of pediatric medulloblastoma experience long-term morbidity
associated with the toxic effects of postoperative radiotherapy (RT). Proton RT limits …

Aim To study incidence, types and degrees of late effects in a geographical cohort of
paediatric medulloblastoma and central nervous system primitive neuroectodermal tumour …