Recent advances of oncolytic virus in cancer therapy

M Mondal, J Guo, P He, D Zhou - Human vaccines & …, 2020 - Taylor & Francis
Oncolytic viruses have been taking the front stage in biological therapy for cancer recently.
The first and most potent virus to be used in oncolytic virotherapy is human adenovirus …

Development of novel vaccine vectors: Chimpanzee adenoviral vectors

J Guo, M Mondal, D Zhou - Human vaccines & …, 2018 - Taylor & Francis
Adenoviral vector has been employed as one of the most efficient means against infectious
diseases and cancer. It can be genetically modified and armed with foreign antigens to elicit …

Non-human primate-derived adenoviruses for future use as oncolytic agents?

STF Bots, RC Hoeben - International Journal of Molecular Sciences, 2020 - mdpi.com
Non-human primate (NHP)-derived adenoviruses have formed a valuable alternative for the
use of human adenoviruses in vaccine development and gene therapy strategies by virtue of …

Nonhuman primate adenoviruses of the human adenovirus B species are potent and broadly acting oncolytic vector candidates

STF Bots, V Kemp, SJ Cramer… - Human Gene …, 2022 - liebertpub.com
The use of human adenoviruses (hAds) as oncolytic agents has demonstrated considerable
potential. However, their efficacy in clinical studies is generally moderate and often varies …

Overview of role of survivin in cancer: expression, regulation, functions, and its potential as a therapeutic target

X Fang, X Cao, J Xiao, Y Hu, M Chen… - Journal of Drug …, 2024 - Taylor & Francis
Survivin holds significant importance as a member of the inhibitor of apoptosis protein (IAP)
family due to its predominant expression in tumours rather than normal terminally …

A potential bat adenovirus-based oncolytic virus targeting canine cancers

H Matsugo, T Kitamura-Kobayashi, H Kamiki… - Scientific reports, 2021 - nature.com
Although a canine adenovirus (CAdV)-based oncolytic virus (OV) candidate targeting canine
tumors has been reported, its oncolytic effect could be attenuated by CAdV vaccine-induced …

[HTML][HTML] Adenovirus-Neutralizing and Infection-Promoting Activities Measured in Serum of Human Brain Cancer Patients Treated with Oncolytic Adenovirus Ad5-∆ 24 …

IH van der Meulen-Muileman… - International Journal of …, 2025 - mdpi.com
Oncolytic adenoviruses derived from human serotype 5 (Ad5) are being developed to treat
cancer. Treatment efficacy could be affected by pre-existing or induced neutralizing …

Chimpanzee adenoviral vector prime-boost regimen elicits potent immune responses against Ebola virus in mice and rhesus macaques

X Yang, X Wang, Y Song, P Zhou, D Li… - Emerging Microbes & …, 2019 - Taylor & Francis
In the last few decades, Ebola virus (EBOV) has emerged periodically and infected people in
Africa, resulting in an extremely high mortality rate. With no available prophylaxis or cure so …

[HTML][HTML] Modern approaches to treating cancer with oncolytic viruses

IV Vorobjeva, OP Zhirnov - Microbiology Independent Research …, 2022 - cyberleninka.ru
According to the World Health Organization, cancer is the second leading cause of death in
the world. This serves as a powerful incentive to search for new effective cancer treatments …

[HTML][HTML] Современные подходы к лечению рака онколитическими вирусами

ИВ Воробьева, ОП Жирнов - Microbiology Independent Research …, 2022 - cyberleninka.ru
По данным Всемирной организации здравоохранения онкологические заболевания
занимают второе место по смертности в мире. Это обстоятельство является мощным …