Type 2 diabetes mellitus (T2DM) is a chronic endocrine disorder due to the reduction of insulin sensitivity and relative deficiency of insulin secretion. Growth differentiation factor 15 …
P Iglesias, RA Silvestre, JJ Díez - Endocrine, 2023 - Springer
Human growth differentiation factor 15 (GDF-15) is a widely distributed protein that has shown to play multiple roles in both physiological and pathological conditions. In healthy …
V Varhegyi, A Modos, D Trager, D Gerszi… - International Journal of …, 2024 - mdpi.com
There is no literature available about the growth differentiation factor-15 (GDF-15) biomarker in combination with mitochondrial DNA (mtDNA) deletions in insulin resistance (IR), and …
MG Mohammad, R Saeed… - Experimental …, 2023 - journals.sagepub.com
Mounting evidence points to a link between growth differentiation factor-15 (GDF15) expression and the onset and progression of diabetes mellitus. However, the exact role of …
Y Sun, X Hu, K Zhang, M Rao, P Yin, R Dong - Cells, 2022 - mdpi.com
Background: The great saphenous vein (GSV) is the most commonly used conduit for coronary arterial bypass graft. However, the status of the GSV, including metabolic …
CA Hoekx, ME Straat, MB Bizino… - Experimental …, 2024 - Wiley Online Library
Abstract Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists induce weight loss in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanism is unclear. Recently, the …
R Qiao, J Guo, C Zhang, S Wang, J Fang… - Critical Reviews in …, 2024 - Taylor & Francis
Diabetes has become a serious public health crisis, presenting significant challenges to individuals worldwide. As the largest organ in the human body, skeletal muscle is a …
Q Wang, M Farhadipour, T Thijs, ER Sosoranga… - Molecular …, 2024 - Elsevier
Objective Growth differentiation factor 15 (GDF15), a stress related cytokine, was recently identified as a novel satiety signal acting via the GFRAL receptor located in the hindbrain …
Aim/hypothesis Growth/differentiation factor 15 (GDF15) is a therapeutic target for a variety of metabolic diseases, including type 1 diabetes (T1D). However, the nausea caused by …