Recent trends in preparation, investigation and application of polysaccharide-based chiral stationary phases for separation of enantiomers in high-performance liquid …

B Chankvetadze - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
This review article summarizes the recent developments in preparation, investigation and
application of polysaccharide-based chiral stationary phases for the separation of …

Column characterization and selection systems in reversed-phase high-performance liquid chromatography

P Žuvela, M Skoczylas, J Jay Liu, T Ba̧czek… - Chemical …, 2019 - ACS Publications
Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most popular
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …

Homochiral metal–organic frameworks for enantioseparation

J Liu, S Mukherjee, F Wang, RA Fischer… - Chemical Society …, 2021 - pubs.rsc.org
Obtaining homochiral compounds is of high importance to human health and environmental
sustainability. Currently, enantioseparation is one of the most effective approaches to obtain …

Chiral stationary phases for liquid chromatography: recent developments

J Teixeira, ME Tiritan, MMM Pinto, C Fernandes - Molecules, 2019 - mdpi.com
The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time

BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

Advances and innovations in liquid chromatography stationary phase supports

K Broeckhoven, G Desmet - Analytical Chemistry, 2020 - ACS Publications
The continuous evolution of stationary phase supports over the past decades have allowed
a vast increase the separation performance in liquid chromatography. As in any …

[HTML][HTML] Recent developments in the high-throughput separation of biologically active chiral compounds via high performance liquid chromatography

C De Luca, S Felletti, FA Franchina, D Bozza… - … of Pharmaceutical and …, 2024 - Elsevier
Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Potency testing of cannabinoids by liquid and supercritical fluid chromatography: Where we are, what we need

S Felletti, C De Luca, A Buratti, D Bozza… - … of Chromatography A, 2021 - Elsevier
Hemp and cannabis industry is undergoing a renewed interest due to legalization of
marijuana (a topic that all countries are discussing, especially in recent years) and the …

Chiral separations in food analysis

G D'Orazio, C Fanali, M Asensio-Ramos… - TrAC Trends in Analytical …, 2017 - Elsevier
The determination of enantiomers is a very important topic in different areas including
pharmaceutical, biomedical, agrochemical and food fields. In fact these compounds possess …

Extra-column band broadening effects in contemporary liquid chromatography: Causes and solutions

G Desmet, K Broeckhoven - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Columns for liquid chromatography produce ever narrower peaks and analysts continue to
push to smaller column diameters to save solvents and have better MS responses. The …