[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives

Y Fan, X Li, L Zhang, S Wan, L Zhang… - Signal transduction and …, 2022 - nature.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

The emergence and epidemic characteristics of the highly mutated SARS‐CoV‐2 Omicron variant

D Tian, Y Sun, H Xu, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
Recently, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
variant (B. 1.1. 529) was first identified in Botswana in November 2021. It was first reported …

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant (B. 1.1. 529) has multiple spike protein
mutations, that contribute to viral escape from antibody neutralization,,–and reduce vaccine …

Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants

HF Tseng, BK Ackerson, Y Luo, LS Sy, CA Talarico… - Nature medicine, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B. 1.1. 529)
variant is highly transmissible with potential immune escape. We conducted a test-negative …

[HTML][HTML] SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron

A Tarke, CH Coelho, Z Zhang, JM Dan, ED Yu… - Cell, 2022 - cell.com
We address whether T cell responses induced by different vaccine platforms (mRNA-1273,
BNT162b2, Ad26. COV2. S, and NVX-CoV2373) cross-recognize early SARS-CoV-2 …

Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …

Current evidence on efficacy of COVID‐19 booster dose vaccination against the Omicron variant: A systematic review

S Chenchula, P Karunakaran… - Journal of medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an ongoing pandemic, which affected
around 45 million confirmed cases of COVID‐19, including more than 6 million deaths …

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines

G McLean, J Kamil, B Lee, P Moore, TF Schulz, A Muik… - MBio, 2022 - Am Soc Microbiol
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …

Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies

X Wang, X Zhao, J Song, J Wu, Y Zhu, M Li… - Emerging microbes & …, 2022 - Taylor & Francis
The massive and rapid transmission of SARS-CoV-2 has led to the emergence of several
viral variants of concern (VOCs), with the most recent one, B. 1.1. 529 (Omicron), which …

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

BJ Willett, J Grove, OA MacLean, C Wilkie… - Nature …, 2022 - nature.com
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health
response to COVID-19. The emergence of hypermutated, increasingly transmissible variants …