Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

Exosome-like systems: nanotechnology to overcome challenges for targeted cancer therapies

J García-Fernández, M de la Fuente Freire - Cancer Letters, 2023 - Elsevier
Exosomes are natural extracellular nanovesicles (30–150 nm in diameter) with the ability to
interact with and be taken up by specific cells. They are being explored as delivery systems …

Recent trends in the use of small extracellular vesicles as optimal drug delivery vehicles in oncology

SK Kumar, MV Sasidhar - Molecular Pharmaceutics, 2023 - ACS Publications
Small extracellular vesicles (sEVs) are produced by most cells and play an important role in
cell-to-cell communication and maintaining cellular homeostasis. Their ability to transfer …

Extracellular vesicles modulate key signalling pathways in refractory wound healing

B Yang, Y Lin, Y Huang, N Zhu, YQ Shen - Burns & Trauma, 2023 - academic.oup.com
Chronic wounds are wounds that cannot heal properly due to various factors, such as
underlying diseases, infection or reinjury, and improper healing of skin wounds and ulcers …

Engineered Extracellular Vesicles: Emerging Therapeutic Strategies for Translational Applications

JN Ziegler, C Tian - International Journal of Molecular Sciences, 2023 - mdpi.com
Extracellular vesicles (EVs) are small, membrane-bound vesicles used by cells to deliver
biological cargo such as proteins, mRNA, and other biomolecules from one cell to another …

Extracellular vesicle contents as non-invasive biomarkers in ovarian malignancies

LA McAlarnen, P Gupta, R Singh, S Pradeep… - Molecular Therapy …, 2022 - cell.com
Ovarian cancer most commonly presents at an advanced stage where survival is
approximately 30% compared with> 80% if diagnosed and treated before disease spreads …

[HTML][HTML] Extracellular Vesicles in Ovarian Cancer: From Chemoresistance Mediators to Therapeutic Vectors

B Muttiah, ND Muhammad Fuad, F Jaafar… - Biomedicines, 2024 - mdpi.com
Ovarian cancer (OC) remains the deadliest gynecological malignancy, with alarming
projections indicating a 42% increase in new cases and a 51% rise in mortality by 2040 …

αvβ3 Receptor-targeted acid-responsive controlled-release endosome escape doxorubicin-loaded liposomes for A549/ADR treatment

H Chen, C Liu, S Yu, H Zhou, F Shafiq… - Colloids and Surfaces A …, 2023 - Elsevier
The emergence of liposomes has provided a breakthrough for the clinical use of highly toxic
chemotherapeutic drugs. However, the clinical effects of conventional drug-loaded …

Hydroxychloroquine enhances cytotoxic properties of extracellular vesicles and extracellular vesicle–mimetic nanovesicles loaded with chemotherapeutics

S Brezgin, A Kostyusheva, N Ponomareva, E Bayurova… - Pharmaceutics, 2023 - mdpi.com
Because of their high biocompatibility, biological barrier negotiation, and functionalization
properties, biological nanoparticles have been actively investigated for many medical …

Non-Coding RNAs Delivery by Small Extracellular Vesicles and Their Applications in Ovarian Cancer

M Liu, X Zhou, J Tang - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Ovarian cancer (OC) is the most fatal gynecological malignancy because of its early
asymptomatic nature and acquired resistance to chemotherapy. Small extracellular vesicles …