Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

Ovarian cancer (OC) represents the main cause of death from gynecological malignancies
in western countries. Altered cellular and mitochondrial metabolism are considered …

Dihydroartemisinin (DHA), a natural product derived from the herbal medicine Artemisia
annua, is recently used as a novel anti-cancer agent. However, some intrinsic …

Mitochondria is a subcellular organelle involved in the pathogenesis of cellular stress,
immune responses, differentiation, metabolic disorders, aging, and death by regulating …

Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics
plays an important role in maintaining mitochondrial homeostasis, and the disorder in …

Sulfur dioxide (SO 2) is a ubiquitous environmental pollutant that has been shown to be toxic
to the male reproductive system, but the underlying mechanism remains unclear. Therefore …

Bile acids (BAs) are amphiphilic steroidal molecules generated from cholesterol in the liver
and facilitate the digestion and absorption of fat-soluble substances in the gut. Some BAs in …

Mitochondria have been identified to be involved in oxidative phosphorylation, lipid
metabolism, cell death, and cell proliferation. Previous studies have demonstrated that …

Mitochondrial autophagy (mitophagy) is very important process for the maintenance of
cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk …

Mitochondrial dysfunction is one of the key mechanisms for developing chronic kidney
disease (CKD). Hyperoxaluria and nephrolithiasis are also associated with mitochondrial …