Consistent evidence associates IGF-1 deficiency and metabolic syndrome. In this review, we
will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its …

Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

This review addresses the possible role of the insulin‐like growth factor (IGF)‐axis in normal
glucose homoeostasis and in the etiopathogenesis of type 2 diabetes. IGF‐I, a peptide …

Insulin-like growth factor (IGF)-binding proteins (IGFBPs) confer temporospatial regulation to
IGF bioactivity. Both stimulatory and inhibitory effects of IGFBPs on IGF actions have been …

Elevated insulin-like growth factor binding protein (IGFBP) levels, including IGFBP-1, occur
in renal failure, and may contribute towards reduced IGF bioactivity in uraemia. The reduced …

Objective. Exercise can enhance growth and development in children, but recent
investigations have revealed an intriguing paradox. Namely, the early (4–5 weeks) response …

The insulin-like growth factors (IGFs), IGF binding proteins (IGFBPs), and IGFBP proteases
regulate somatic growth and cellular proliferation both in vivo and in vitro. IGFs are potent …

The insulin-like growth factors (IGFs), insulin-like growth factors binding proteins (IGFBPs),
and the IGFBP proteases (BP-Pr) are involved in the regulation of somatic growth and …

Muscle wasting and weakness are common in many disease states and conditions including
aging, cancer cachexia, sepsis, denervation, disuse, inactivity, burns, HIV-acquired …

The insulin-like growth factors (IGFs), insulin-like growth factor binding proteins (IGFBPs),
and the IGFBP proteases are involved in the regulation of somatic growth and cellular prolif …