Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft

J Kazi, R Sen, S Ganguly, T Jha, S Ganguly… - International Journal of …, 2020 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green tea
exhibits significant anti-cancer potential over a wide range of cancer cells. We have …

Apigenin-loaded PLGA-DMSA nanoparticles: a novel strategy to treat melanoma lung metastasis

R Sen, S Ganguly, S Ganguly, MC Debnath… - Molecular …, 2021 - ACS Publications
The flavone apigenin (APG), alone as well as in combination with other chemotherapeutic
agents, is known to exhibit potential anticancer effects in various tumors and inhibit growth …

Ursolic Acid Loaded PLGA Nanoparticles: in vitro and in vivo Evaluation to Explore Tumor Targeting Ability on B16F10 Melanoma Cell Lines

R Baishya, DK Nayak, D Kumar, S Sinha… - Pharmaceutical …, 2016 - Springer
Purpose Ursolic acid (UA), a pentacyclic triterpenoid extracted from plants, shows promising
inhibitory effect in different tumor bearing cell lines. In the present study we fabricated UA …

Design of 5-fluorouracil (5-FU) loaded, folate conjugated peptide linked nanoparticles, a potential new drug carrier for selective targeting of tumor cells

J Kazi, R Mukhopadhyay, R Sen, T Jha, S Ganguly… - …, 2019 - pubs.rsc.org
In the present investigation folate peptide (FA-Pep) conjugated 5-fluorouracil (5-FU) loaded
nanoparticles were synthesized and their tumor targeting potentiality was monitored by …

Synthesis and preliminary evaluation of a 99mTc‐labeled folate‐PAMAM dendrimer for FR imaging

M Song, Z Guo, M Gao, C Shi, D Xu… - Chemical Biology & …, 2017 - Wiley Online Library
Folate receptor is an ideal target for tumor‐specific diagnostic and therapeutic. The aim of
this study was to synthesize 99mTc‐labeled folate‐polyamidoamine dendrimer modified …

Development of a peptide-based bifunctional chelator conjugated to a cytotoxic drug for the treatment of melanotic melanoma

RH Gaonkar, R Baishya, B Paul, S Dewanjee… - …, 2018 - pubs.rsc.org
The cytotoxic drug gemcitabine (GEM) has been conjugated to receptor-binding peptides to
target melanoma tumors. A hexapeptide having a Lys–Gly–His–Lys sequence (pep-1), an …

Synthesis, Characterization, and Initial Biological Evaluation of [99mTc]Tc‐Tricarbonyl‐labeled DPA‐α‐MSH Peptide Derivatives for Potential Melanoma Imaging

F Gao, W Sihver, R Bergmann, B Belter… - …, 2018 - Wiley Online Library
Abstract α‐Melanocyte stimulating hormone (α‐MSH) derivatives target the melanocortin‐1
receptor (MC1R) specifically and selectively. In this study, the α‐MSH‐derived peptide NAP …

[HTML][HTML] Nanomolar photodynamic activity of porphyrins bearing 1, 4, 7-trioxanonyl and 2-methyl-5-nitroimidazole moieties against cancer cells

M Wierzchowski, D Łażewski, T Tardowski… - … of Photochemistry and …, 2020 - Elsevier
Despite the continuous development of medicine, there is still a lack of effective and fully
safe protocols for the treatment of neoplastic diseases. The drug-drug conjugates approach …

Изучение аллергизирующих свойств радиофармпрепарата «Наноколлоид, 99mТc–Al2O3» в эксперименте

НВ Варламова, ЕС Стасюк, АА Тицкая… - Современные …, 2015 - cyberleninka.ru
Цель исследования—в эксперименте оценить аллергизирующие свойства нового
наноколлоидного препарата на основе мечен-ного технецием-99m гамма-оксида …

Exploring the Potential of 99mTc(CO)3-Labeled Triazolyl Peptides for Tumor Diagnosis

RH Gaonkar, S Ganguly, R Baishya… - Cancer Biotherapy …, 2016 - liebertpub.com
In recent years the authors have reported on 99mTc (CO) 3-labeled peptides that serve as
carriers for biomolecules or radiopharmaceuticals to the tumors. In continuation of that work …