Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Versican belongs to the family of the large aggregating chondroitin sulfate proteoglycans
located primarily within the extracellular matrix (ECM). Versican, like other members of its …

The targeting of molecular repertoires to complex systems rather than biochemically pure
entities is an accessible approach that can identify proteins of biological interest. We have …

Extracellular matrix proteins are thought to provide a rigid mechanical anchor that supports
and guides migrating and rolling cells,,,. Here we examine the mechanical properties of the …

Background The Ehlers–Danlos syndrome is a heritable connective-tissue disorder caused
by defects in fibrillar-collagen metabolism. Mutations in the type V collagen genes account …

Considerable advances have been made in our knowledge of the molecular structure of cell
adhesion molecules, their binding sites, and adhesion complexes. For the cadherins, protein …

The tenascins are a family of large extracellular matrix proteins with at least three members:
tenascin-X (TNX) 1–3, tenascin-C (TNC, or cytotactin) 4–6 and tenascin-R (TN-R, or restrict …

Signaling through growth factor receptors controls such diverse cell functions as
proliferation, migration, and differentiation. A critical question has been how the activation of …

In this review we discuss the major morphogenetic and regulative events that control
myocardial progenitor cells from the time that they delaminate from the epiblast in the …

This book explains and reviews some of the significant events involved in human
implantation and the establishment of the placenta in the uterus. This critical phase in …