Formulation and evaluation of niosomal alendronate sodium encapsulated in polymeric microneedles: In vitro studies, stability study and cytotoxicity study

A Zaid Alkilani, H Abu-Zour, A Alshishani… - Nanomaterials, 2022 - mdpi.com
The aim of this study is to design and evaluate a transdermal delivery system for
alendronate sodium (ALS) loaded with nanocarrier to improve its permeability and prolong …

Radioiodinated acemetacin loaded niosomes as a dual anticancer therapy

MA Shewaiter, AA Selim, YM Moustafa, S Gad… - International Journal of …, 2022 - Elsevier
A niosomal formula of acemetacin was developed to improve its tumor targeting and radio-
kinetic evaluation was performed using 131 I. Niosomes were prepared by ether injection …

Architecting novel multilayer nanosponges for co-administration of two drugs managing high-risk type II diabetes mellitus patients suffering from cardiovascular …

RW Hammad, RAB Sanad, NS Abdelmalak… - International Journal of …, 2022 - Elsevier
Nanosponges are porous solid nanoparticles composed of hyper-cross-linked polymers that
serve as specific micro-domains designed for the co-encapsulation of two drugs with …

Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique

MA Shewaiter, AA Selim, HM Rashed… - Journal of Cancer …, 2023 - Springer
Background This work aimed to prepare niosomal formulations of an anticancer agent
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …

Understanding the Pharmacological and Nanotechnological Facets of Dipeptidyl Peptidase-4 Inhibitors in Type II Diabetes Mellitus: a Paradigm in Therapeutics

N Tiwary, N Sharma, S Singh, T Behl, I Zahoor - BioNanoScience, 2024 - Springer
The worldwide incidence of type 2 diabetes mellitus (T2DM), a chronic metabolic disorder, is
increasing rapidly. A newer category of oral hypoglycemic medications called dipeptidyl …

Water in nigella oil microemulsion for enhanced oral bioavailability of linagliptin

RK Eid, MF Arafa, GM El Maghraby - Drug Delivery and Translational …, 2024 - Springer
Linagliptin is hydrophilic antidiabetic with poor oral bioavailability due to poor permeability
and pre-systemic metabolism. The objective was to assess w/o microemulsion for enhanced …

Niosomes as a Novel Pharmaceutical Carrier: Structure, Classification and Preparation Methods

MA Mahmoud - Records of Pharmaceutical and Biomedical …, 2023 - rpbs.journals.ekb.eg
Niosomes are non-ionic surfactant vesicles obtained by a hydrating mixture of cholesterol
and nonionic surfactants. It can be used as a carrier of an amphiphilic and lipophilic drugs …

Development of Linagliptin Ultra Fine Solid Supersaturated Bio-SNEDDS Using Triangular Mixture Design for Enhancement of Oral Bioavailability: Impact of P-gp …

HM Mansour, AEGHA El-Gawad… - Journal of …, 2023 - repository.journal4submission.com
Linagliptin (LIN) is a newly developed dipeptidyl peptidase 4 (DPP-4) inhibitor oral
antidiabetic drug. LIN is considered a P-gp substrate, thus suffers from poor bioavailability (< …

In vitro and Ex vivo Analysis of Pitavastatin-Loaded Liposomes for the Treatment of Hyperlipidemia

S Delwar, S Islam, ME Al Mamun, N Akter… - … University Journal of …, 2023 - banglajol.info
Pitavastatin is a BCS class II drug with low solubility and high permeability. So, the purpose
of the study was to develop and characterize pitavastatin-loaded liposomes to achieve …

Niosomes as a Novel Pharmaceutical Carrier: Structure, Classification and Preparation Methods

MA Shewaiter, AA Selim, HM Rashed, YM Moustafa… - journals.ekb.eg
Niosomes are non-ionic surfactant vesicles obtained by a hydrating mixture of cholesterol
and nonionic surfactants. It can be used as a carrier of an amphiphilic and lipophilic drugs …