[HTML][HTML] OATP2B1–The underrated member of the organic anion transporting polypeptide family of drug transporters?
J Kinzi, M Grube, HEM Zu Schwabedissen - Biochemical Pharmacology, 2021 - Elsevier
The organic anion transporting polypeptide 2B1 (OATP2B1) was one of the first cloned
members of the SLCO family. However, its physiological and pharmacological role is still …
members of the SLCO family. However, its physiological and pharmacological role is still …
Role of organic anion-transporting polypeptides (OATPs) in cancer therapy
The superfamily of organic anion-transporting polypeptides (OATPs, gene symbol SLCO)
includes important transporters handling a variety of endogenous and xenobiotic substrates …
includes important transporters handling a variety of endogenous and xenobiotic substrates …
Tumor‐specific expression of organic anion‐transporting polypeptides: Transporters as novel targets for cancer therapy
V Buxhofer-Ausch, L Secky, K Wlcek… - Journal of drug …, 2013 - Wiley Online Library
Members of the organic anion transporter family (OATP) mediate the transmembrane uptake
of clinical important drugs and hormones thereby affecting drug disposition and tissue …
of clinical important drugs and hormones thereby affecting drug disposition and tissue …
Defect‐Assisted Loading and Docking Conformations of Pharmaceuticals in Metal–Organic Frameworks
Understanding of drug–carrier interactions is essential for the design and application of
metal–organic framework (MOF)‐based drug‐delivery systems, and such drug–carrier …
metal–organic framework (MOF)‐based drug‐delivery systems, and such drug–carrier …
Organic anion transporting polypeptide 2B1–more than a glass-full of drug interactions
SJ McFeely, L Wu, TK Ritchie, J Unadkat - Pharmacology & therapeutics, 2019 - Elsevier
The importance of uptake transporters in determining drug disposition is increasingly
appreciated. While the focus of regulatory agencies worldwide has been on the hepatic …
appreciated. While the focus of regulatory agencies worldwide has been on the hepatic …
Mechanisms of nonsteroidal anti-inflammatory drugs in cancer prevention
A Umar, VE Steele, DG Menter, ET Hawk - Seminars in oncology, 2016 - Elsevier
Various clinical and epidemiologic studies show that nonsteroidal anti-inflammatory drugs
(NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer …
(NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer …
[HTML][HTML] Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver
TT Li, JX An, JY Xu, BG Tuo - World Journal of Clinical Cases, 2019 - ncbi.nlm.nih.gov
Organic anion transporters (OATs) and organic anion transporter polypeptides (OATPs) are
classified within two SLC superfamilies, namely, the SLC22A superfamily and the SLCO …
classified within two SLC superfamilies, namely, the SLC22A superfamily and the SLCO …
ABCC4 copy number variation is associated with susceptibility to esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is the eighth most common cause of cancer-
related death worldwide. However, previous genome-wide single nucleotide polymorphism …
related death worldwide. However, previous genome-wide single nucleotide polymorphism …
Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy—Modulators of Cellular Entry or Pharmacokinetics?
K Brecht, AM Schäfer, HE Meyer zu Schwabedissen - Cancers, 2020 - mdpi.com
Solute carrier transporters comprise a large family of uptake transporters involved in the
transmembrane transport of a wide array of endogenous substrates such as hormones …
transmembrane transport of a wide array of endogenous substrates such as hormones …