Microfluidics for sperm analysis and selection

R Nosrati, PJ Graham, B Zhang, J Riordon… - Nature Reviews …, 2017 - nature.com
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells

C González-Marín, J Gosálvez, R Roy - International journal of molecular …, 2012 - mdpi.com
Concentration, motility and morphology are parameters commonly used to determine the
fertilization potential of an ejaculate. These parameters give a general view on the quality of …

Sperm selection with hyaluronic acid improved live birth outcomes among older couples and was connected to sperm DNA quality, potentially affecting all treatment …

R West, A Coomarasamy, L Frew, R Hutton… - Human …, 2022 - academic.oup.com
STUDY QUESTION What effects did treatment using hyaluronic acid (HA) binding/selection
prior to ICSI have on clinical outcomes in the Hyaluronic Acid Binding sperm Selection …

Sperm DNA integrity and male fertility in farm animals: a review

A Kumaresan, M Das Gupta, TK Datta… - Frontiers in veterinary …, 2020 - frontiersin.org
The accurate prediction of male fertility is of major economic importance in the animal
breeding industry. However, the results of conventional semen analysis do not always …

Making immotile sperm motile using high-frequency ultrasound

A Vafaie, MR Raveshi, C Devendran, R Nosrati… - Science …, 2024 - science.org
Sperm motility is a natural selection with a crucial role in both natural and assisted
reproduction. Common methods for increasing sperm motility are by using chemicals that …

Rapid selection of sperm with high DNA integrity

R Nosrati, M Vollmer, L Eamer, MC San Gabriel… - Lab on a Chip, 2014 - pubs.rsc.org
Sperm selection is essential to assisted reproductive technology (ART), influencing
treatment outcomes and the health of offspring. The fundamental challenge of sperm …

[HTML][HTML] Separation efficiency of a microfluidic sperm sorter to minimize sperm DNA damage

K Shirota, F Yotsumoto, H Itoh, H Obama, N Hidaka… - Fertility and sterility, 2016 - Elsevier
Objective To evaluate whether microfluidic sperm sorters (MFSSs) allow effective recovery of
sorted motile sperm without DNA damage compared with the centrifugation and swim-up …

An update on oxidative damage to spermatozoa and oocytes

CS Opuwari, RR Henkel - BioMed research international, 2016 - Wiley Online Library
On the one hand, reactive oxygen species (ROS) are mandatory mediators for essential
cellular functions including the function of germ cells (oocytes and spermatozoa) and …

Oxidative Stress in Oocytes and Embryo Development: Implications for In Vitro Systems

J Lin, L Wang - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: To improve the outcomes of in vitro culture of human oocytes and embryos, the
dynamic balance and roles of reactive oxygen species (ROS) in folliculogenesis and embryo …

[HTML][HTML] Shorter abstinence decreases sperm deoxyribonucleic acid fragmentation in ejaculate

J Gosálvez, M González-Martínez… - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To evaluate the relationship between duration of sexual abstinence and sperm
selection on sperm DNA fragmentation (SDF). DESIGN: Prospective study based on …