Biochar produced from corn stover is a renewable, plentiful source of carbon that is a
potential substitute for binder/filter media for water or beverage purification applications …

Regulatory science based pharmaceutical development and product manufacturing is highly
recommended by the authorities nowadays. The aim of this study was to adapt regulatory …

The development of new drugs is often hindered by low solubility in water, a problem
common to nearly 90% of natural and/or synthetic molecules in the discovery pipeline …

The aim of this study was to develop oral lyophilisates with improved meloxicam (MEL)
dissolution, optimizing each step of the preparation by design of experiments. First …

In this study, the time-dependent evolution of amorphous probucol nanoparticles was
characterized by cryogenic transmission electron microscopy (cryo-TEM) and atomic force …

Pharmaceutical powder carriers are often used to prevent agglomeration of a micronized
drug in the co-milling process. Twenty-four pharmaceutical excipients were subjected to …

Nanocrystal is widely applied to improve the dissolution of poorly water-soluble drugs. We
aimed to prepare meloxicam (MLX) nanocrystals using the bead mill method, followed by …

Co-milling of a drug with a co-former is an efficient technique to improve the solubility of
drugs. Besides the particle size reduction, the co-milling process induces a structural …

Nowadays, the intranasal route has become a reliable alternative route for drug
administration to the systemic circulation or central nervous system. However, there are no …

In order to investigate the correlation among energy input–related, drug-related, and
stabilizer-related aspects for both top-down and bottom-up nanocrystal production …