Members of the aspartase/fumarase superfamily share a common tertiary and quaternary
fold, as well as a similar active site architecture; the superfamily includes aspartase …

The medium-resolution structure of adenylosuccinate lyase (PurB) from the bacterial
pathogen Staphylococcus aureus in complex with AMP is presented. Oxalate, which is likely …

For nearly 30 years, coenzyme M (CoM) was assumed to be present solely in methanogenic
archaea. In the late 1990s, CoM was reported to play a role in bacterial propene …

The availability of genomic data from extinct homini such as Neanderthals has caused a
revolution in palaeontology allowing the identification of modern human-specific protein …

Adenylosuccinate lyase (PurB) catalyzes two distinct reactions in the purine nucleotide
biosynthetic pathway using the same active site. The ability to recognize two different sets of …

The purine-biosynthetic pathway is ultimately responsible for the generation of inosine 50-
monophosphate from-d-ribose-5-phosphate (Zhang et al., 2008) and provides the essential …

For nearly 30 years, coenzyme M (CoM) was assumed to be present solely in methanogenic
archaea. In the late 1990s, CoM was reported to play a role in bacterial propene …

A tuberculose humana (TB) é uma doença infectocontagiosa provocada principalmente
pelo Mycobacterium tuberculosis e permanece sendo um importante problema mundial de …

This chapter contains sections titled: Introduction Addition of Ammonia and Amines to
Fumaric Acid: l‐Aspartase‐Fumarase Superfamily Other Aspartase/Fumarase Family …