Health effects associated with exposure to secondhand smoke: a Burden of Proof study

LS Flor, JA Anderson, N Ahmad, A Aravkin, S Carr… - Nature Medicine, 2024 - nature.com
Despite a gradual decline in smoking rates over time, exposure to secondhand smoke
(SHS) continues to cause harm to nonsmokers, who are disproportionately children and …

Childhood asthma: pathogenesis and phenotypes

MW Pijnenburg, U Frey, JC De Jongste… - European Respiratory …, 2022 - Eur Respiratory Soc
In the pathogenesis of asthma in children there is a pivotal role for a type 2 inflammatory
response to early life exposures or events. Interactions between infections, atopy, genetic …

Cohort profile update: the Bern Basel infant lung development cohort

Y Salem, J Jakob, R Steinberg… - International journal …, 2024 - academic.oup.com
This is an update on the Bern Basel Infant Lung Development (BILD-) cohort profile
published in 2012. 1 The BILD-cohort is a prospective birth cohort study with ongoing …

Dynamic transitions of pediatric sepsis: a Markov chain analysis

SL Kausch, JM Lobo, MC Spaeder, B Sullivan… - Frontiers in …, 2021 - frontiersin.org
Pediatric sepsis is a heterogeneous disease with varying physiological dynamics associated
with recovery, disability, and mortality. Using risk scores generated from a sepsis prediction …

Exercise science and child health: a tale of many journeys

DM Cooper - Pediatric exercise science, 2019 - journals.humankinetics.com
Children are the most naturally physically active human beings; reduced physical activity is
a cardinal sign of childhood disease, and exercise testing provides mechanistic insights into …

Symptom trajectories in infancy for the prediction of subsequent wheeze and asthma in the BILD and PASTURE cohorts: a dynamic network analysis

U Nahum, O Gorlanova, F Decrue, H Oller… - The Lancet Digital …, 2024 - thelancet.com
Background Host and environment early-life risk factors are associated with progression of
wheezing symptoms over time; however, their individual contribution is relatively small. We …

Individual illness dynamics: an analysis of children with sepsis admitted to the pediatric intensive care unit

SL Kausch, B Sullivan, MC Spaeder… - PLOS Digital …, 2022 - journals.plos.org
Illness dynamics and patterns of recovery may be essential features in understanding the
critical illness course. We propose a method to characterize individual illness dynamics in …

Pollen exposure is associated with risk of respiratory symptoms during the first year of life

A Gisler, M Eeftens, K de Hoogh, D Vienneau… - Allergy, 2022 - Wiley Online Library
Background Pollen exposure is associated with respiratory symptoms in children and adults.
However, the association of pollen exposure with respiratory symptoms during infancy, a …

Antibiotics in pregnancy influence nasal microbiome and respiratory morbidity in infancy

C Rüttimann, A Nissen-Kratzert, N Mostacci… - ERJ Open …, 2023 - Eur Respiratory Soc
Background The effects of prenatal antibiotic exposure on respiratory morbidity in infancy
and the involved mechanisms are still poorly understood. We aimed to examine whether …

Dynamics of inhaled corticosteroid use are associated with asthma attacks

J Lee, J Huvanandana, JM Foster, HK Reddel… - Scientific reports, 2021 - nature.com
Inhaled corticosteroids (ICS) suppress eosinophilic airway inflammation in asthma, but
patients may not adhere to prescribed use. Mean adherence—averaging total doses taken …