Oral tumor heterogeneity, its implications for patient monitoring and designing anti-cancer strategies
R Mishra - Pathology-Research and Practice, 2024 - Elsevier
Oral cancer tumors occur in the mouth and are mainly derived from oral mucosa linings. It is
one of the most common and fatal malignant diseases worldwide. The intratumor …
one of the most common and fatal malignant diseases worldwide. The intratumor …
[HTML][HTML] Potential of melatonin to reverse epigenetic aberrations in oral cancer: new findings
It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis
and functional changes, both of which are essential for the initiation and completion of the …
and functional changes, both of which are essential for the initiation and completion of the …
Effect of valproic acid on extrinsic and intrinsic apoptotic pathways, cell viability and apoptosis in hepatocellular carcinoma PLC/PRF5 cell line
Y Lu, Y Liu, K Zhang, L Jiang - Cellular and Molecular Biology, 2022 - mail.cellmolbiol.org
Inhibitors of histone deacetylase enzymes induce various molecular and extracellular effects
that lead to their anticancer role. In this study, the result of valproic acid on the expression of …
that lead to their anticancer role. In this study, the result of valproic acid on the expression of …
Proteolysis-targeting chimeras targeting epigenetic modulators: a promising strategy for oral cancer therapy
VP Jayaseelan, K Loganathan, A Pandi… - …, 2023 - Taylor & Francis
Oral squamous cell carcinoma (OSCC) is the most common form of malignancy accounting
for 80–90% of all head and neck cancer. OSCC is associated with high morbidity, mortality …
for 80–90% of all head and neck cancer. OSCC is associated with high morbidity, mortality …
[HTML][HTML] Differential Expression of DNA Methyltransferase (DNMT1 and DNMT3), Histone Deacetylase (HDAC1 and HDAC2), and Upstream Target Regulators MiR …
T Holloway, K Kingsley - Targets, 2024 - mdpi.com
Epigenetic modulation of DNA and histones facilitated by and histone deacetylases (HDAC)
is associated with the development and progression of many cancers, although less is …
is associated with the development and progression of many cancers, although less is …
Selinexor assists vorinostat in inhibiting HDAC activity via promoting the accumulation of maspin in the nucleus of oral tongue squamous cell carcinoma cells
F Yuan, J Yong, X Liu, Y Wang - Cytotechnology, 2023 - Springer
Oral tongue squamous cell carcinoma (OTSCC) is the most common oral cancer with a low
overall survival rate, necessitating effective treatments. This study reports the anti-OTSCC …
overall survival rate, necessitating effective treatments. This study reports the anti-OTSCC …
组蛋白去乙酰基转移酶2 在胰腺癌中作用机制及治疗的研究进展
陈磊， 何超， 刘攀， 付强， 张宏伟， 秦涛 - 肝胆胰外科杂志, 2023 - gdy.qk.wmu.edu.cn
胰腺癌是最常见的恶性肿瘤之一, 其发病率逐年增加, 位列癌症致死原因第5 位.
起病隐匿是胰腺癌的显著特点, 多数患者就诊时即为晚期, 丧失手术机会, 错过最佳治疗时机 …
起病隐匿是胰腺癌的显著特点, 多数患者就诊时即为晚期, 丧失手术机会, 错过最佳治疗时机 …