More than a quarter of the world's population is at risk of infection with the soil-transmitted
helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator …

Objective To evaluate efficacies of anthelmintic drugs against soil transmitted helminths in
terms of cure rates and egg reduction rates. Design Systematic review and network meta …

Mass drug administration (MDA) is a means of delivering safe and inexpensive essential
medicines based on the principles of preventive chemotherapy, where populations or sub …

Helminth infections are responsible for a considerable public health burden, yet the current
drug armamentarium is small. Given the high cost of drug discovery and development, the …

Highlights•Gastrointestinal nematodes are resistant to available anthelmintics.•No new
anthelmintic on the market for several years.•A target-based approach, drug repurposing or …

Background Existing anthelmintic drugs (eg, albendazole and mebendazole) have low
efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is …

On May 22, 2001, a resolution passed during the 54th World Health Assembly (WHA 54.19)
took an historic step toward reducing the morbidity and mortality associated with the world's …

Background The soil-transmitted helminths (STH), Ascaris lumbricoides, Trichuris trichiura
and hookworms, infect 1.5 billion people worldwide and cause an estimated burden of 3.3 …

Background Robust reference values for fecal egg count reduction (FECR) rates of the most
widely used anthelmintic drugs in preventive chemotherapy (PC) programs for controlling …

The soil-transmitted helminths (STHs), Ascaris lumbricoides, hookworm and Trichuris
trichiura are common in areas with warm and moist climates with little access to adequate …