▪ Abstract Dendritic cells (DCs) have several functions in innate and adaptive immunity. In
addition, there is increasing evidence that DCs in situ induce antigen-specific …

A properly functioning adaptive immune system signifies the best features of life. It is diverse
beyond compare, tolerant without fail, and capable of behaving appropriately with a myriad …

The mannose receptor recognizes the patterns of carbohydrates that decorate the surfaces
and cell walls of infectious agents. This macrophage and dendritic cell pattern-recognition …

Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

Many receptors for endocytosis recycle into and out of cells through early endosomes. We
now find in dendritic cells that the DEC-205 multilectin receptor targets late endosomes or …

The avoidance of autoimmunity requires mechanisms to actively silence or tolerize self
reactive T cells in the periphery. During infection, dendritic cells are not only capturing …

Substantial numbers of dendritic cells (DCs) are found in the T‐cell areas of peripheral
lymphoid organs such as the spleen, lymph node and Peyer's patch. By electron microscopy …

Abstract DC-SIGN is a C-type lectin, highly expressed on the surface ofimmature dendritic
cells (DCs), that mediates efficient infection of Tcells in trans by its ability to bind HIV-1, HIV …

The induction of antigen‐specific T cell tolerance and its maintenance in the periphery is
critical for the prevention of autoimmunity. Recent evidence shows that dendritic cells (DC) …

We have shown previously that granulocyte-macrophage colony-stimulating factor-
stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that …