Local anesthetic-induced neurotoxicity

M Verlinde, MW Hollmann, MF Stevens… - International journal of …, 2016 - mdpi.com
This review summarizes current knowledge concerning incidence, risk factors, and
mechanisms of perioperative nerve injury, with focus on local anesthetic-induced …

The effects of ghrelin on inflammation and the immune system

D Baatar, K Patel, DD Taub - Molecular and cellular endocrinology, 2011 - Elsevier
A number of hormones and metabolic mediators signal the brain of changes in the body's
energy status and when an imbalance occurs; the brain coordinates the appropriate …

Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway

Y Yang, L Wang, C Zhang, Y Guo, J Li… - Chemical Biology & …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive
impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with …

Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system

N Hattori - Growth Hormone & IGF Research, 2009 - Elsevier
Immune and neuroendocrine systems have bidirectional communications. Growth hormone
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …

[HTML][HTML] Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice

PE Porporato, N Filigheddu, S Reano… - The Journal of …, 2013 - Am Soc Clin Investig
Cachexia is a wasting syndrome associated with cancer, AIDS, multiple sclerosis, and
several other disease states. It is characterized by weight loss, fatigue, loss of appetite, and …

Cholinesterases and the fine line between poison and remedy

CN Pope, S Brimijoin - Biochemical pharmacology, 2018 - Elsevier
Abstract Acetylcholinesterase (AChE, EC 3.1. 1.7) and butyrylcholinesterase (BChE, EC 3.1.
1.8) are related enzymes found across the animal kingdom. The critical role of …

Ghrelin signaling in the ventral hippocampus stimulates learned and motivational aspects of feeding via PI3K-Akt signaling

SE Kanoski, SM Fortin, KM Ricks, HJ Grill - Biological psychiatry, 2013 - Elsevier
BACKGROUND: The stomach-derived hormone ghrelin drives higher-order feeding
processes related to food reward and food seeking via central nervous system signaling at …

The extra-hypothalamic actions of ghrelin on neuronal function

ZB Andrews - Trends in neurosciences, 2011 - cell.com
Ghrelin is a peptide hormone produced and secreted in the stomach. Numerous studies
over the past decade demonstrate its importance in food intake, body-weight regulation and …

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

AK Walker, PD Rivera, Q Wang, JC Chuang… - Molecular …, 2015 - nature.com
Augmenting hippocampal neurogenesis represents a potential new strategy for treating
depression. Here we test this possibility by comparing hippocampal neurogenesis in …

Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation

M Moon, HG Kim, L Hwang, JH Seo, S Kim… - Neurotoxicity …, 2009 - Springer
Ghrelin is an endogenous ligand for growth hormone (GH) secretagogue receptor 1a (GHS-
R1a) and is produced and released mainly from the stomach. It was recently demonstrated …