Metal-free multicomponent syntheses of pyridines

C Allais, JM Grassot, J Rodriguez… - Chemical …, 2014 - ACS Publications
They react according to a succession of mono-or bimolecular processes to form at the end
one product that incorporates important portions and functionalities of the starting materials …

Multicomponent reaction design in the quest for molecular complexity and diversity

E Ruijter, R Scheffelaar… - Angewandte Chemie …, 2011 - Wiley Online Library
Multicomponent reactions have become increasingly popular as tools for the rapid
generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and …

Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles

G Guillena, DJ Ramon, M Yus - Chemical reviews, 2010 - ACS Publications
The chemistry of amines, amides, and other nitrogencontaining compounds plays a central
role in the organic synthesis. In fact, the first synthesized organic compound was urea. 1 The …

Alcohols as Electrophiles in C C Bond‐Forming Reactions: The Hydrogen Autotransfer Process

G Guillena, DJ Ramón, M Yus - … Chemie International Edition, 2007 - Wiley Online Library
The hydrogen autotransfer process involves an initial oxidative hydrogen elimination,
followed by different types of reactions, and is completed with a reductive hydrogen addition …

All-carbon quaternary stereogenic centers in acyclic systems through the creation of several C–C bonds per chemical step

I Marek, Y Minko, M Pasco, T Mejuch… - Journal of the …, 2014 - ACS Publications
In the past few decades, it has become clear that asymmetric catalysis is one of the most
powerful methods for the construction of carbon–carbon as well as carbon–heteroatom …

Cerium (IV) ammonium nitrate as a catalyst in organic synthesis

V Sridharan, JC Menéndez - Chemical reviews, 2010 - ACS Publications
Cerium belongs to the family of the lanthanides, which constitute (together with scandium
and yttrium) the so-called rare earth elements. Cerium is the most abundant of these …

Enantioselective direct aldol reaction: the blossoming of modern organocatalysis

G Guillena, C Najera, DJ Ramon - Tetrahedron: Asymmetry, 2007 - Elsevier
The use of simple (S)-proline as catalyst for the intermolecular direct aldol reaction at the
beginning of this century became a true milestone in the growth of organocatalysis as a …

Rapid four-component reactions in water: synthesis of pyranopyrazoles

G Vasuki, K Kumaravel - Tetrahedron Letters, 2008 - Elsevier
Rapid four-component reactions in water: synthesis of pyranopyrazoles - ScienceDirect
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Organocatalytic enantioselective multicomponent reactions (OEMCRs)

G Guillena, DJ Ramon, M Yus - Tetrahedron: Asymmetry, 2007 - Elsevier
The achieved level of expertise in organocatalytic processes has allowed synthetic chemists
to apply this useful synthetic strategy to enantioselective multicomponent reactions …

Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions

MJ Aliaga, DJ Ramón, M Yus - Organic & biomolecular chemistry, 2010 - pubs.rsc.org
Impregnated copper on magnetite is a versatile, inexpensive and simple catalyst for the
selective multicomponent reaction of terminal alkynes, aldehydes and secondary amines to …