IL‐1β Drives Production of FGF‐23 at the Onset of Chronic Kidney Disease in Mice

Q McKnight, S Jenkins, X Li, T Nelson… - Journal of Bone and …, 2020 - academic.oup.com
ABSTRACT FGF‐23 has arisen as an early biomarker of renal dysfunction, but at the onset
of chronic kidney disease (CKD), data suggest that FGF‐23 may be produced independently …

Osteoporosis associated with chronic kidney disease

SM Ott, GJ Elder - Marcus and Feldman's Osteoporosis, 2021 - Elsevier
Chronic kidney disease (CKD) is associated with high rates of fracture, cardiovascular
events, and mortality. The pathophysiology is complex, including reduced levels of Klotho …