Epidemiology of atrial fibrillation: geographic/ecological risk factors, age, sex, genetics

J Zhang, SP Johnsen, Y Guo… - Cardiac …, 2021 - cardiacep.theclinics.com
Atrial fibrillation (AF) is the most common arrhythmia with ever-increasing public health
impact. 1 Over 50 years of observation in the Framingham Heart Study (FHS), there is a 4 …

Genetics and epigenetics of atrial fibrillation

E Lozano-Velasco, D Franco, A Aranega… - International journal of …, 2020 - mdpi.com
Atrial fibrillation (AF) is known to be the most common supraventricular arrhythmia affecting
up to 1% of the general population. Its prevalence exponentially increases with age and …

[PDF][PDF] 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

P Kirchhof, S Benussi, D Kotecha… - Polish Heart …, 2016 - journals.viamedica.pl
Komisję ESC ds. Wytycznych Postępowania nadzoruje i koordynuje przygotowywanie
nowych wytycznych i stanowisk przez grupy robocze i inne grupy ekspertów. Komitet jest …

[PDF][PDF] Guía ESC 2016 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración con la EACTS

S Benussi, D Kotecha, A Ahlsson… - Rev Esp …, 2017 - sedeelectronica.comcordoba.com
Se recomienda a los profesionales de la salud que tengan en consideración la presente
guía de la ESC/EACTS en la toma de decisiones clínicas en su ejercicio diario, así como en …

Genetics of atrial fibrillation

J Feghaly, P Zakka, B London, CA MacRae… - Journal of the …, 2018 - Am Heart Assoc
Background Atrial fibrillation (AF) is a common arrhythmia seen in clinical practice.
Occasionally, no common risk factors are present in patients with this arrhythmia. This …

Improved prediction of drug‐induced Torsades de Pointes through simulations of dynamics and machine learning algorithms

MC Lancaster, EA Sobie - Clinical Pharmacology & …, 2016 - Wiley Online Library
The ventricular arrhythmia Torsades de Pointes (TdP) is a common form of drug‐induced
cardiotoxicity, but prediction of this arrhythmia remains an unresolved issue in drug …

Mechanisms and drug development in atrial fibrillation

D Calvo, D Filgueiras-Rama, J Jalife, LL Isom - Pharmacological Reviews, 2018 - Elsevier
Atrial fibrillation is a highly prevalent cardiac arrhythmia and the most important cause of
embolic stroke. Although genetic studies have identified an increasing assembly of AF …

Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

IE Christophersen, MS Olesen, B Liang… - European heart …, 2013 - academic.oup.com
Aims Genetic factors may be important in the development of atrial fibrillation (AF) in the
young. KCNA5 encodes the potassium channel α-subunit KV1. 5, which underlies the …

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement …

S Tzeis, EP Gerstenfeld, J Kalman, EB Saad… - Europace, 2024 - academic.oup.com
In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based
safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007 …

Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review

D Fatkin, IG Huttner, JC Kovacic, JG Seidman… - Journal of the American …, 2019 - jacc.org
Precision medicine promises to dramatically improve patient outcomes and reduce health
care costs through a shift in focus from disease treatment to prevention and individualized …