Congenital lung malformations

F Pederiva, SS Rothenberg, N Hall… - Nature Reviews …, 2023 - nature.com
Congenital lung malformations (CLMs) are rare developmental anomalies of the lung,
including congenital pulmonary airway malformations (CPAM), bronchopulmonary …

Pulmonary invasive mucinous adenocarcinoma

WC Chang, YZ Zhang, AG Nicholson - Histopathology, 2024 - Wiley Online Library
Invasive mucinous adenocarcinoma (IMA) is a relatively rare subtype of lung
adenocarcinoma, composed of goblet and/or columnar tumour cells containing abundant …

Pleuropulmonary blastoma in pediatric lung lesions

SM Kunisaki, DR Lal, JM Saito, ME Fallat… - …, 2021 - publications.aap.org
BACKGROUND: Pediatric lung lesions are a group of mostly benign pulmonary anomalies
with a broad spectrum of clinical disease and histopathology. Our objective was to evaluate …

Congenital lung anomalies in adults

M Mestas Nuñez, G Dulcich, CS Restrepo… - …, 2024 - pubs.rsna.org
Congenital lung anomaly (CLA) refers to a rare group of malformations that are typically
identified prenatally or in early childhood. However, a significant proportion of cases evade …

Defining the spatial landscape of KRAS mutated congenital pulmonary airway malformations: a distinct entity with a spectrum of histopathologic features

ND Nelson, F Xu, P Chandrasekaran, LA Litzky… - Modern …, 2022 - nature.com
The potential pathogenetic mechanisms underlying the varied morphology of congenital
pulmonary airway malformations (CPAMs) have not been molecularly determined, but a …

Novel molecular and phenotypic insights into congenital lung malformations

DT Swarr, WH Peranteau, J Pogoriler… - American Journal of …, 2018 - atsjournals.org
Rationale: Disruption of normal pulmonary development is a leading cause of morbidity and
mortality in infants. Congenital lung malformations are a unique model to study the …

[HTML][HTML] Early KRAS oncogenic driver mutations in nonmucinous tissue of congenital pulmonary airway malformations as an indicator of potential malignant behavior

SM Hermelijn, JL Wolf, TD den Toom, RMH Wijnen… - Human Pathology, 2020 - Elsevier
The potential for malignant degeneration is the most common reason for some practitioners
to resect asymptomatic congenital pulmonary airway malformations (CPAMs). We aimed to …

Morphologic features in congenital pulmonary airway malformations and pulmonary sequestrations correlate with mutation status: a mechanistic approach to …

ND Nelson, F Xu, WH Peranteau, M Li… - The American Journal …, 2023 - journals.lww.com
Congenital pulmonary airway malformations (CPAMs) have a range of morphologies with
varying cyst sizes and histologic features (types 1 to 3). Evidence suggested they arise …

Mucinous adenocarcinoma arising in congenital pulmonary airway malformation: clinicopathological analysis of 37 cases

WC Chang, YZ Zhang, JL Wolf, SM Hermelijn… - …, 2021 - Wiley Online Library
Aims Mucinous adenocarcinoma arising in congenital pulmonary airway malformation
(CPAM) is a rare complication, with little being known about its natural course. The aims of …

Accuracy of chest computed tomography in distinguishing cystic pleuropulmonary blastoma from benign congenital lung malformations in children

AJ Engwall-Gill, SS Chan, KP Boyd, JM Saito… - JAMA network …, 2022 - jamanetwork.com
Importance The ability of computed tomography (CT) to distinguish between benign
congenital lung malformations and malignant cystic pleuropulmonary blastomas (PPBs) is …