In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …

Tuberculosis is primarily a disease of the lung, and dissemination of the disease depends
on productive infection of this critical organ. Upon aerosol infection with Mycobacterium …

Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

The macrophage mannose receptor (MR, CD206) is a C-type lectin expressed
predominantly by most tissue macrophages, dendritic cells and specific lymphatic or …

Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …

Approximately one third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of tuberculosis. This bacterium has an unusual lipid-rich …

Tuberculosis is still a major health problem in the world. Initial interactions between
Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent …

Tuberculosis (TB) is a leading cause of death worldwide despite the availability of effective
chemotherapy for over 60 years. Although Mycobacterium bovis bacillus Calmette-Guérin …

Lungs are directly exposed to the air, have enormous surface area, and enable gas
exchange in air-breathing animals. They are constantly 'attacked'by microbes from both …

Phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium
tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their …