Immunogenicity and Safety Following 1 Dose of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults: A Phase 3 Trial

TF Schwarz, SJ Hwang, P Ylisastigui… - The Journal of …, 2024 - academic.oup.com
Background The recently approved AS01E-adjuvanted respiratory syncytial virus (RSV)
prefusion F protein–based vaccine for older adults (RSVPreF3 OA) demonstrated high …

The Impact of Immune System Aging on Infectious Diseases

E Quiros-Roldan, A Sottini, PG Natali, L Imberti - Microorganisms, 2024 - mdpi.com
Immune system aging is becoming a field of increasing public health interest because of
prolonged life expectancy, which is not paralleled by an increase in health expectancy. As …

Noninferior Immunogenicity and Consistent Safety of Respiratory Syncytial Virus Prefusion F Protein Vaccine in Adults 50–59 Years Compared to≥ 60 Years of Age

M Ferguson, TF Schwarz, SA Núñez… - Clinical Infectious …, 2024 - academic.oup.com
Background The adjuvanted respiratory syncytial virus (RSV) prefusion F protein–based
vaccine (RSVPreF3 OA) is approved in adults aged≥ 60 years. We evaluated RSVPreF3 …

Nasopharyngeal and Peripheral Blood Type II Interferon Signature Evaluation in Infants during Respiratory Syncytial Virus Infection

F Savino, M Dini, A Clemente, C Calvi, A Pau… - Medicina, 2024 - mdpi.com
Background and Objectives: In this study, we applied one-step real time rt-PCR technology
type II INF signature to blood and nasopharyngeal (NPS) swabs of acute early recovery …

Multiple Questions About Protection From Respiratory Syncytial Virus

SA Plotkin - The Pediatric Infectious Disease Journal, 2024 - journals.lww.com
After innumerable years of frustration with regard to the inability to protect against respiratory
syncytial virus (RSV) infections, the ground-breaking discovery by McCool and colleagues at …