A review of Glycogen Synthase Kinase-3 (GSK3) inhibitors for cancers therapies

R Thapa, G Gupta, AA Bhat, WH Almalki… - International journal of …, 2023 - Elsevier
The intricate molecular pathways governing cancer development and progression have
spurred intensive investigations into novel therapeutic targets. Glycogen Synthase Kinase-3 …

Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review

MS Hussain, G Gupta, M Afzal, SM Alqahtani… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …

Recent developments and challenges in molecular-targeted therapy of non-small-cell lung cancer

S Rohilla, M Singh, SI Alzarea… - Journal of …, 2023 - dl.begellhouse.com
Treatment of lung cancer with conventional therapies, which include radiation, surgery, and
chemotherapy results in multiple undesirable adverse or side effects. The major clinical …

Chronic atrophic gastritis: a review

Y Li, R Xia, B Zhang, C Li - Journal of Environmental Pathology …, 2018 - dl.begellhouse.com
Chronic atrophic gastritis is a generally asymptomatic condition of great importance because
it develops into gastric cancer in a number of patients. It is described as an atrophy of the …

Janus kinase/signal transducers and activator of transcription (JAK/STAT) and its role in Lung inflammatory disease

M Purohit, G Gupta, O Afzal, ASA Altamimi… - Chemico-biological …, 2023 - Elsevier
A key signaling channel for the signal transduction of several crucial cytokines implicated in
sepsis is the JAK/STAT system. Once cytokines attach to the proper receptors, JAK kinases …

Unlocking the secrets: Volatile Organic Compounds (VOCs) and their devastating effects on lung cancer

MS Hussain, G Gupta, R Mishra, N Patel… - … -Research and Practice, 2024 - Elsevier
Lung cancer (LCs) is still a serious health problem globally, with many incidences attributed
to environmental triggers such as Volatile Organic Compounds (VOCs). VOCs are a broad …

PI3K/Akt/mTOR pathways inhibitors with potential prospects in non-small-cell lung cancer

KS Alharbi, MAJ Shaikh, WH Almalki… - Journal of …, 2022 - dl.begellhouse.com
Lung cancer is the leading cause of cancer-related mortality across the globe. The most
prevalent pathological form of lung cancer is non-small-cell lung cancer (NSCLC). Elevated …

A review on protective role of genistein against oxidative stress in diabetes and related complications

L Weng, F Zhang, R Wang, W Ma, Y Song - Chemico-biological interactions, 2019 - Elsevier
Diabetes mellitus (DM) is metabolism related problems that share the phenotype of
hyperglycemia, which is triggered by a complicated interaction of hereditary and …

Janus kinase-signal transducer and activator of transcription inhibitors for the treatment and management of cancer

FA Rizwi, M Abubakar, ER Puppala… - Journal of …, 2023 - dl.begellhouse.com
ABSTRACT According to the World Health Organization (WHO), cancer is the second-
highest cause of mortality worldwide, killing nearly 9.6 million people annually. Despite the …

Combinational effect of curcumin and metformin against gentamicin‐induced nephrotoxicity: Involvement of antioxidative, anti‐inflammatory and antiapoptotic pathway

L Cao, D Zhi, J Han, S Kumar Sah… - Journal of food …, 2019 - Wiley Online Library
Gentamicin (GM) is an antibiotic related to aminoglycoside group that is used in treating
Gram‐negative bacterial infections. However, treatment with gentamicin is considered to be …