This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of
metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease …

The fact that aluminium (Al) and lead (Pb) are both toxic metals to living organisms,
including human beings, was discovered a long time ago. Even when Al and Pb can reach …

Mounting evidences support the idea that endogenous 'biometals', such as copper, iron, zinc
and exogenous ones such as aluminum, can be involved as factors or cofactors in the …

Amyloids can have normal biological functions. 1r3 However, amyloidogenic proteins can
also form unwanted oligomeric or polymeric aggregates when disturbed from their native …

Metal toxicity poses a potential global threat to the environment and living beings. Their
numerous agricultural, medical, industrial, domestic, and technological applications result in …

In the last few years, various studies have been providing evidence that metal ions are
critically involved in the pathogenesis of major neurological diseases (Alzheimer …

Aluminum is a ubiquitously abundant nonessential element. Aluminum has been associated
with neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral …