Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …

Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

Major depressive disorder (MDD) is associated with an increased risk of brain atrophy,
aging-related diseases, and mortality. We examined potential advanced brain aging in adult …

Major depressive disorder (MDD) is characterized by psychological and physiological
manifestations contributing to the disease severity and outcome. In recent years, several …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Biological clocks have been developed at different molecular levels and were found to be
more advanced in the presence of somatic illness and mental disorders. However, it is …

Schizophrenia is a complex psychiatric disorder where genetic, epigenetic, and
environmental factors play a role in disease onset, course of illness, and treatment outcome …

Major depressive disorder (MDD) presents different clinical features in women and men,
with women being more affected and responding differently to antidepressant treatment …

Early adverse experience is related to psychiatric illness that occurs decades later. The
mechanisms underlying this phenomenon have not been fully identified. There is a …