The therapy of pulmonary hypertension has evolved rapidly in the last 10 years from the use
of non-selective vasodilators to drugs that specifically target pulmonary vasodilation …

Pulmonary hypertension is a devastating disorder, characterized by vascular proliferation,
intimal hypertrophy and vasoconstriction. In this disorder, alterations in the nitric oxide …

Background—Pulmonary hypertension (PH) secondary to left heart failure portends a poor
prognosis and is a relative contraindication to heart transplantation at many centers. We …

Pulmonary hypertension (PH) is a multifactorial, progressive disease with poor outcomes.
Group 2 PH is defined by pulmonary vascular disease with elevated pulmonary capillary …

DMD is a devastatingly progressive muscle wasting disorder of childhood that significantly
shortens life expectancy. Despite efforts to develop an effective therapy that dates back over …

The fate of functional tricuspid regurgitation (TR) after closure of a secundum atrial septal
defect (ASD) without any corrective tricuspid valve (TV) surgery remains unclear. We …

Pulmonary hypertension (PH) due to left heart failure is becoming increasingly prevalent
and is associated with poor outcome. The precise pathophysiological mechanisms behind …

OBJECTIVES Unresponsive pulmonary hypertension (PH) may contraindicate heart
transplant since it implies poor early outcomes. The present study reports the effectiveness …

INTRODUCTION: Severe pulmonary hypertension with no response to vasodilators on an
acute hemodynamic study is a contraindication to cardiac transplantation. The development …

Background: Pre‐operative elevated pulmonary vascular resistance (PVR) has been
associated with increased right ventricular failure and mortality after heart transplantation …