High‐density lipoprotein: A potent inhibitor of inflammation

AJ Murphy, KJ Woollard - Clinical and Experimental …, 2010 - Wiley Online Library
Inflammation is an important process, driving the progression of atherosclerosis. Stemming
inflammation may be a mechanism to inhibit the progression of this disease. 2. High‐density …

The anti inflammatory effects of high density lipoproteins

AJ Murphy, JPF Chin-Dusting… - Current medicinal …, 2009 - ingentaconnect.com
It is well recognised that increased levels of high density lipoprotein (HDL) protect against
atherosclerosis and correlate with improved prognosis for vascular disease associated …

Platelet proteome dynamics in hibernating 13-lined ground squirrels

S Cooper, PA Wilmarth, JM Cunliffe… - Physiological …, 2021 - journals.physiology.org
Hibernating mammals undergo a dramatic drop in temperature and blood flow during torpor,
yet avoid stasis blood clotting through mechanisms that remain unspecified. The effects of …

Effect of resveratrol on platelet activation in hypercholesterolemic rats: CD40–CD40L system as a potential target

AY Göçmen, D Burgucu… - … Physiology, Nutrition, and …, 2011 - cdnsciencepub.com
Our aim was to investigate whether trans-resveratrol (t-resveratrol), a red wine constituent
known for its cardioprotective effects, was able to influence CD40 ligand (CD40L) and its …

Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet–leukocyte aggregate formation occur simultaneously in hyperlipidemia?

A Sener, D Ozsavci, R Oba, GY Demirel, F Uras… - Clinical …, 2005 - Elsevier
OBJECTIVES:: The circulating lipoproteins may cause some abnormalities in platelet
composition and function in hypercholesterolemia. The aim of this study was to investigate …

High density lipoprotein: assembly, structure, cargo, and functions

AJ Murphy - International Scholarly Research Notices, 2013 - Wiley Online Library
Cardiovascular disease (CVD) is the leading cause of death globally. For close to four
decades, we have known that high density lipoprotein (HDL) levels are inversely correlated …

Association of plasma growth arrest-specific protein 6 (Gas6) concentrations with albuminuria in patients with type 2 diabetes

A Erek-Toprak, O Bingol-Ozakpinar, Z Karaca… - Renal …, 2014 - Taylor & Francis
Aims: New biomarkers are required to detect diabetic nephropathy earlier in persons with
type 2 diabetes mellitus. Recent experimental studies indicate that growth arrest-specific …

Expression of cholesterol sulfotransferase (SULT2B1b) in human platelets

H Yanai, NB Javitt, Y Higashi, H Fuda, CA Strott - Circulation, 2004 - Am Heart Assoc
Background—Cholesterol sulfate, the most important sterol sulfate in the human circulation,
has emerged as a multifaceted molecule. Among its many demonstrated regulatory actions …

High‐density lipoprotein 3 and apolipoprotein A‐I alleviate platelet storage lesion and release of platelet extracellular vesicles

A Pienimaeki‐Roemer, A Fischer, M Tafelmeier… - …, 2014 - Wiley Online Library
Background Stored platelet (PLT) concentrates (PLC s) for transfusion develop a PLT
storage lesion (PSL), decreasing PLT viability and function with profound lipidomic changes …

Flow cytometric assay of platelet glycoprotein receptor numbers in hypercholesterolemia

D Ozsavci, T Yardimci, GY Demirel, E Demiralp, F Uras… - Platelets, 2002 - Taylor & Francis
In this study, platelet glycoprotein (Gp) receptor numbers were measured by a flow
cytometric assay using Cytoquant Gp in seven hypercholesterolemic and five normal …