Transdermal delivery for gene therapy

P Singh, I Muhammad, NE Nelson, KTM Tran… - Drug delivery and …, 2022 - Springer
Gene therapy is a critical constituent of treatment approaches for genetic diseases and has
gained tremendous attention. Treating and preventing diseases at the genetic level using …

Targeting genetic modifiers of HBG gene expression in sickle cell disease: the miRNA option

A Starlard-Davenport, Q Gu, BS Pace - Molecular Diagnosis & Therapy, 2022 - Springer
Sickle cell disease (SCD) is one of the most common inherited hemoglobinopathy disorders
that affects millions of people worldwide. Reactivation of HBG (HBG1, HBG2) gene …

Banana fruit (Musa sp.) DNA-magnetite nanoparticles: Synthesis, characterization, and biocompatibility assays on normal and cancerous cells

D Arregui-Almeida, M Coronel, K Analuisa… - Plos one, 2024 - journals.plos.org
Magnet-mediated gene therapy has gained considerable interest from researchers as a
novel alternative for treating genetic disorders, particularly through the use of …

Gene therapy in the management of Parkinson's disease: potential of GDNF as a promising therapeutic strategy

T Behl, I Kaur, A Kumar, V Mehta… - Current Gene …, 2020 - ingentaconnect.com
The limitations of conventional treatment therapies in Parkinson's disorder, a common
neurodegenerative disorder, lead to the development of an alternative gene therapy …

[HTML][HTML] The significance of chemical transfection/transduction enhancers in promoting the viral vectors-assisted gene delivery approaches: A focus on potentials for …

S Najafi, A Rahimpour, H Ahmadieh… - Electronic Journal of …, 2024 - Elsevier
Viral vectors are among the main approaches currently used in studies for executing gene
delivery to target cells. During the past decades of active studies in gene therapy, including …

Next Generation Therapeutic Strateg‐Es: Evolving cancer immunotherapy through agents that Engage, Expand and Enable the anti‐tumor immune response

B Wolfson, JW Hodge - ImmunoMedicine, 2021 - Wiley Online Library
The development and FDA approval of immune checkpoint blocking antibodies have
brought new light to cancer immunotherapy. While immune checkpoint blockade (ICB) has …

Nanobiotechnology-Modified Cellular and Molecular Therapy as a Novel Approach for Autoimmune Diabetes Management

PV Lawand, S Desai - Pharmaceutical Nanotechnology, 2022 - ingentaconnect.com
Several cellular and molecular therapies such as stem cell therapy, cell replacement
therapy, gene modification therapy, and tolerance induction therapy have been researched …