New vaccine technologies to combat outbreak situations

S Rauch, E Jasny, KE Schmidt, B Petsch - Frontiers in immunology, 2018 - frontiersin.org
Ever since the development of the first vaccine more than 200 years ago, vaccinations have
greatly decreased the burden of infectious diseases worldwide, famously leading to the …

[HTML][HTML] COVID-19 vaccines: Current status and implication for use in Indonesia

Y Ophinni, AS Hasibuan, A Widhani… - Acta Medica …, 2020 - actamedindones.org
Abstract The coronavirus disease 2019 (COVID-19) has inflicted catastrophic damages in
public health, economic and social stability—putting life globally on hold in 2020 and …

Randomized trial of vaccines for Zaire Ebola virus disease

PREVAC Study Team - New England Journal of Medicine, 2022 - Mass Medical Soc
Background Questions remain concerning the rapidity of immune responses and the
durability and safety of vaccines used to prevent Zaire Ebola virus disease. Methods We …

Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

Safety and immunogenicity of a 2-dose heterologous vaccine regimen with Ad26. ZEBOV and MVA-BN-Filo Ebola vaccines: 12-month data from a phase 1 …

G Mutua, O Anzala, K Luhn, C Robinson… - The Journal of …, 2019 - academic.oup.com
Abstract Background During the 2014 West African Ebola outbreak, Ebola vaccine
development was accelerated. The phase 1 VAC52150EBL1003 study was performed to …

Ebola vaccine trials: progress in vaccine safety and immunogenicity

KM Matz, A Marzi, H Feldmann - Expert review of vaccines, 2019 - Taylor & Francis
Introduction: Ebolaviruses are non-segmented negative-strand RNA viruses in the
Filoviridae family that cause a neglected infectious disease designated as Ebola virus …

Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens

A Fathi, C Dahlke, MM Addo - Human vaccines & …, 2019 - Taylor & Francis
The devastating Ebola virus (EBOV) outbreak in West Africa in 2013–2016 has flagged the
need for the timely development of vaccines for high-threat pathogens. To be better …

Development of pandemic vaccines: ERVEBO case study

J Wolf, R Jannat, S Dubey, S Troth, MT Onorato… - Vaccines, 2021 - mdpi.com
Preventative vaccines are considered one of the most cost-effective and efficient means to
contain outbreaks and prevent pandemics. However, the requirements to gain licensure and …

Effectiveness of COVID‑19 vaccines and their challenges

G Marfe, S Perna, AK Shukla - Experimental and …, 2021 - spandidos-publications.com
At the end of 2019, a new disease recognized such as severe acute respiratory syndrome
(SARS), was reported in Wuhan, China. This disease was caused by an unknown SARS …

[HTML][HTML] Use of Ebola vaccine: recommendations of the advisory committee on immunization practices, United States, 2020

MJ Choi - MMWR. Recommendations and Reports, 2021 - cdc.gov
This report summarizes the recommendations of the Advisory Committee on Immunization
Practices (ACIP) for use of the rVSVΔG-ZEBOV-GP Ebola vaccine (Ervebo) in the United …