Coumarin heterocyclic derivatives: chemical synthesis and biological activity

FG Medina, JG Marrero, M Macías-Alonso… - Natural product …, 2015 - pubs.rsc.org
Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

[HTML][HTML] Fructose as a key player in the development of fatty liver disease

M Basaranoglu, G Basaranoglu… - World journal of …, 2013 - ncbi.nlm.nih.gov
We aimed to investigate whether increased consumption of fructose is linked to the
increased prevalence of fatty liver. The prevalence of nonalcoholic steatohepatitis (NASH) is …

Identification of quinoline-chalcone hybrids as potential antiulcer agents

KV Sashidhara, SR Avula, V Mishra, GR Palnati… - European journal of …, 2015 - Elsevier
Antiulcer activity of novel quinoline-chalcone hybrids (13–37) was investigated. Among
them, eight compounds (14, 16, 17, 23, 29, 31, 32 and 35) were found to be active in various …

Discovery of coumarin–monastrol hybrid as potential antibreast tumor-specific agent

KV Sashidhara, SR Avula, K Sharma, GR Palnati… - European journal of …, 2013 - Elsevier
Development of new, targeted antibreast cancer drug which can treat both the hormone
receptor (positive and negative) breast cancers is a very challenging task. The concept of …

A review of bisindolylmethane as an important scaffold for drug discovery

S Imran, M Taha… - Current Medicinal …, 2015 - ingentaconnect.com
Bisindolylmethane and its derivatives are pharmacologically active and applicable in the
field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities …

Graphene oxide: An efficient recyclable solid acid for the synthesis of bis (indolyl) methanes from aldehydes and indoles in water

Y Wang, R Sang, Y Zheng, L Guo, M Guan… - Catalysis Communications, 2017 - Elsevier
An efficient synthesis of bis (indolyl) methanes from aldehydes with indoles through
graphene oxide-catalyzed Friedel-Crafts alkylation is developed. The reaction proceeds in …

Design and synthesis of new series of coumarin–aminopyran derivatives possessing potential anti-depressant-like activity

KV Sashidhara, RK Modukuri, S Singh, KB Rao… - Bioorganic & Medicinal …, 2015 - Elsevier
A new series of coumarin based aminopyran derivatives were designed, synthesized and
evaluated for their preclinical antidepressant effect on Swiss albino mice. Among the series …

Visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles: a facile access to 3, 3′ bisindolylmethanes

Y Zhang, X Yang, H Zhou, S Li, Y Zhu… - Organic Chemistry …, 2018 - pubs.rsc.org
A visible light-induced aerobic oxidative cross-coupling of glycine derivatives with indoles
has been developed to efficiently synthesize 3, 3′-bisindolylmethanes (BIMs). The reaction …

Humic acid: A Biodegradable Organocatalyst for Solvent‐free Synthesis of Bis (indolyl) methanes, Bis (pyrazolyl) methanes, Bis‐coumarins and Bis‐lawsones

B Mitra, P Ghosh - ChemistrySelect, 2021 - Wiley Online Library
Humic acid, a biodegradable, non‐toxic and easily accessible high molecular weight
organocatalyst has been explored for the straightforward and environmentally benign …

Molecular iodine-catalyzed selective C-3 benzylation of indoles with benzylic alcohols: a greener approach toward benzylated indoles

P Bhattacharjee, U Bora - ACS omega, 2019 - ACS Publications
Iodine-catalyzed selective C-3 benzylation of indoles with benzylic alcohols is developed.
The reaction proceeds with molecular iodine as the catalyst under ligand-, metal-, and base …