Reactive oxygen species (ROS) are a family of highly reactive molecules with numerous,
often pleiotropic functions within the cell and the organism. Due to their potential to destroy …

Dendritic cells (DCs) are antigen-presenting cells (APCs) that are essential for the activation
of immune responses. In various malignancies, these immunostimulatory properties are …

In this review, we explore the role of dendritic cell subsets in the development of tissue‐
specific autoimmune diseases. From the increasing list of dendritic cell subclasses, it is …

Vitamin D (VitD) is a hormone primarily synthesized in human skin under the stimulation of
ultraviolet radiation. Beyond its endocrine role in bone metabolism, VitD is endowed with …

In recent years, it has been an explosion of information regarding the role of various myeloid
cells in liver pathology. Macrophages and dendritic cell (DC) play crucial roles in multiple …

The year 2021 marks the 100th anniversary of the momentous discovery of insulin. Through
years of research and discovery, insulin has evolved from poorly defined crude extracts of …

Antigen presentation is no longer the exclusive domain of cells of hematopoietic origin.
Recent works have demonstrated that lymph node stromal cell (LNSC) populations, such as …

The use of autologous tolerogenic dendritic cells (tolDC) has become a promising
alternative for the treatment of autoimmune diseases. Among the different strategies …

Systematic lupus erythematosus (SLE) is an autoimmune disease reflecting an imbalance
between effector and regulatory immune responses. Dendritic cells (DC) are a link between …

The TGF-β superfamily consists of a large group of pleiotropic cytokines that are involved in
the regulation of many developmental, physiological and pathological processes. Dendritic …