Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

Regulation and gene expression of heme synthesis under heavy metal exposure-review

A Schauder, A Avital, Z Malik - Journal of Environmental …, 2010 - dl.begellhouse.com
Environmental pollution of heavy metals is very abundant nowadays from industry,
chemicals, old paints, and pipes or resulting from previous contaminants accumulating in the …

Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies

AV Skalny, M Aschner, Y Jiang, YG Gluhcheva… - Advances in …, 2021 - Elsevier
Recent studies have demonstrated that brain may be considered as the target for aluminium
(Al) toxicity, resulting in development of neurodegenerative and neurodevelopmental …

Fenugreek seed powder attenuated aluminum chloride-induced tau pathology, oxidative stress, and inflammation in a rat model of alzheimer's disease 1

A Prema, A Justin Thenmozhi… - Journal of …, 2017 - content.iospress.com
Alzheimer's disease (AD) is a common neurodegenerative disorder that mainly affects the
aged population and is characterized by the progressive loss of the hippocampal and …

Neuroprotective effect of curcumin in arsenic-induced neurotoxicity in rats

RS Yadav, RK Shukla, ML Sankhwar, DK Patel… - Neurotoxicology, 2010 - Elsevier
Our recent studies have shown that arsenic-induced neurobehavioral toxicity is protected by
curcumin by modulating oxidative stress and dopaminergic functions in rats. In addition, the …

[HTML][HTML] The potential role of pomegranate and its nano-formulations on cerebral neurons in aluminum chloride induced Alzheimer rat model

MS Almuhayawi, WS Ramadan, S Harakeh… - Saudi journal of …, 2020 - Elsevier
The oxidative stress leading to degenerative changes in the brain of Alzheimer's disease
(AD) is evident. Our aim was to evaluate the therapeutic and protective effects of …

Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors

B Sharma, PM Sharma - Toxicology and applied pharmacology, 2013 - Elsevier
Arsenic toxicity has been reported to damage all the major organs including the brain and
vasculature. Dementia including Alzheimer's disease (AD) and vascular dementia (VaD) are …

Comparative Biochemical Profiling of Aluminum Chloride and Sodium Azide Induced Neuroinflammation and Cardiometabolic Disturbance

K Jabeen, K Rehman, FR Awan, B Aslam… - ACS …, 2022 - ACS Publications
Comorbidities in human beings signify the numerous risk factors that increase the
incidences of neuro-and cardio-metabolic disorders. Experimental models depicting …

[HTML][HTML] Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction

OME Abdel-Salam, MES El-Shamarka… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): To investigate the potential therapeutic effect of Bougainvillea spectabilis
flower decoction on aluminum chloride (AlCl 3)-induced neurotoxicity. Materials and …

[HTML][HTML] Protective effect of hot peppers against amyloid β peptide and brain injury in AlCl3-induced Alzheimer's disease in rats

OME Abdel-Salam, MES El-Shamarka… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): This study investigated the therapeutic effect of red hot pepper (Capsicum
annuum) methanolic extract in induced Alzheimer's disease using AlCl 3 in male rats …