Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor
B Troppmann, G Kleinau, G Krause… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND In recent years it became evident that several types of the luteinizing
hormone/choriogonadotrophin receptor (LHCGR) exist. In addition to the classical receptor …
hormone/choriogonadotrophin receptor (LHCGR) exist. In addition to the classical receptor …
Hormonal, functional and genetic biomarkers in controlled ovarian stimulation: tools for matching patients and protocols
Variability in the subfertile patient population excludes the possibility of a single approach to
controlled ovarian stimulation (COS) covering all the requirements of a patient. Modern …
controlled ovarian stimulation (COS) covering all the requirements of a patient. Modern …
Genomic features defining exonic variants that modulate splicing
A Woolfe, JC Mullikin, L Elnitski - Genome biology, 2010 - Springer
Background Single point mutations at both synonymous and non-synonymous positions
within exons can have severe effects on gene function through disruption of splicing …
within exons can have severe effects on gene function through disruption of splicing …
Individualised controlled ovarian stimulation (iCOS): maximising success rates for assisted reproductive technology patients
E Bosch, D Ezcurra - Reproductive Biology and Endocrinology, 2011 - Springer
Background In the last two decades, pregnancy rates for patients undergoing in-vitro
fertilisation (IVF) have significantly increased. Some of the major advances responsible for …
fertilisation (IVF) have significantly increased. Some of the major advances responsible for …
Diseases caused by mutations in luteinizing hormone/chorionic gonadotropin receptor
J Qiao, B Han - Progress in molecular biology and translational …, 2019 - Elsevier
Accumulating evidence showed that the luteinizing hormone/chorionic gonadotropin
receptor (LHCGR) is an essential regulator of sexual development and reproduction from …
receptor (LHCGR) is an essential regulator of sexual development and reproduction from …
Genetics of ovarian hyperstimulation syndrome
B Rizk - Reproductive biomedicine online, 2009 - Elsevier
Ovarian hyperstimulation syndrome (OHSS) is typically iatrogenic following the
administration of gonadotrophins. Sporadic and familial cases of spontaneous OHSS have …
administration of gonadotrophins. Sporadic and familial cases of spontaneous OHSS have …
Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation
L Riccetti, F De Pascali, L Gilioli, D Santi… - Best practice & research …, 2017 - Elsevier
Highlights•FSHB c.-211G> T, FSHR p. Asn680Ser, and c.-29G> A SNPs are OR and COS
response markers.•No solid association between LHCGR/LHB SNPs and OR or COS …
response markers.•No solid association between LHCGR/LHB SNPs and OR or COS …
New insights into the evolution of chorionic gonadotrophin
A Henke, J Gromoll - Molecular and cellular endocrinology, 2008 - Elsevier
The glycoprotein hormones luteinizing hormone (LH) and chorionic gonadotrophin (CG) are
crucial for reproduction, as LH induces sex hormone production and ovulation, and CG is …
crucial for reproduction, as LH induces sex hormone production and ovulation, and CG is …
Novel mutations of the LHCGR gene in two families with 46, XY DSD causing Leydig cell hypoplasia I
HA Hassan, ML Essawi, MK Mekkawy, I Mazen - Hormones, 2020 - Springer
Purpose Leydig cell hypoplasia is a rare autosomal recessive 46, XY disorder of sexual
development (DSD). It is caused by homozygous or compound heterozygous inactivating …
development (DSD). It is caused by homozygous or compound heterozygous inactivating …