Background Methodological studies–studies that evaluate the design, analysis or reporting
of other research-related reports–play an important role in health research. They help to …

Objective Determine the effectiveness of intraosseous basivertebral nerve radiofrequency
neurotomy for the treatment of chronic low back pain with type 1 or 2 Modic changes. Design …

BACKGROUND The Open Payments Database (OPD) started in 2013 to combat financial
conflicts of interest between physicians and medical industry. OBJECTIVE To evaluate the …

Objective Determine the effectiveness of spinal cord stimulation (SCS) for the treatment of
axial low back pain (LBP) with or without leg pain. Design Systematic review. Subjects …

Methods| Using a 20% national sample of Medicare beneficiaries, we examined individuals
65 years or older who underwent outpatient surgical procedures between January 1, 2009 …

Introduction Systematic reviews (SR) and systematic reviews with meta-analysis (SRMA)
can constitute the highest level of research evidence. Such evidence syntheses are relied …

Abstract The International Committee of Medical Journal Editors requires authors to disclose
all financial conflicts of interest (COI) that can be perceived as influencing the related trials …

Purpose Platelet-rich plasma (PRP) represents a highly profitable biological therapy.
Platelet-rich plasma is widely used to treat musculoskeletal disorders despite mixed …

Background Neurosurgical randomized controlled trials (RCTs) are difficult to carry out due
to the low incidence of certain diseases, heterogeneous disease phenotypes, and ethical …

Background Industry through its funding of research and through its relationships with study
authors can influence the results of research. Most journals have policies for reporting …