Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations
Individuals with SARS-CoV-2 infection can develop symptoms that persist well beyond the
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …
Simvastatin in critically ill patients with Covid-19
REMAP-CAP Investigators - New England Journal of Medicine, 2023 - Mass Medical Soc
Background The efficacy of simvastatin in critically ill patients with coronavirus disease 2019
(Covid-19) is unclear. Methods In an ongoing international, multifactorial, adaptive platform …
(Covid-19) is unclear. Methods In an ongoing international, multifactorial, adaptive platform …
Damage to endothelial barriers and its contribution to long COVID
X Wu, M Xiang, H Jing, C Wang, VA Novakovic, J Shi - Angiogenesis, 2024 - Springer
The world continues to contend with COVID-19, fueled by the emergence of viral variants. At
the same time, a subset of convalescent individuals continues to experience persistent and …
the same time, a subset of convalescent individuals continues to experience persistent and …
Clinical course and management of COVID-19 in the era of widespread population immunity
The clinical implications of COVID-19 have changed since SARS-CoV-2 first emerged in
humans. The current high levels of population immunity, due to prior infection and/or …
humans. The current high levels of population immunity, due to prior infection and/or …
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support–free days in patients hospitalized with COVID-19: a …
S Florescu, D Stanciu, M Zaharia, A Kosa, D Codreanu… - Jama, 2023 - jamanetwork.com
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor
clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin …
clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin …
[图书][B] Clinical anesthesia
PG Barash - 2009 - books.google.com
The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …
COVID-19 annual update: A narrative review
M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human Genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
[HTML][HTML] Outpatient treatment of Covid-19 with metformin, ivermectin, and fluvoxamine and the development of Long Covid over 10-month follow-up
Background Long Covid is an emerging chronic illness potentially affecting millions,
sometimes preventing the ability to work or participate in normal daily activities. COVID-OUT …
sometimes preventing the ability to work or participate in normal daily activities. COVID-OUT …
ACE2-dependent and-independent SARS-CoV-2 entries dictate viral replication and inflammatory response during infection
Excessive inflammation is the primary cause of mortality in patients with severe COVID-19,
yet the underlying mechanisms remain poorly understood. Our study reveals that ACE2 …
yet the underlying mechanisms remain poorly understood. Our study reveals that ACE2 …