Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

The prevalence of obesity has been steadily increasing over the past few decades in several
developed and developing countries, with resultant hazardous health implications …

The NF-κB transcription factor pathway is a crucial regulator of inflammation and immune
responses. Additionally, aberrant NF-κB signaling has been identified in many types of …

The activation of nuclear factor-kappaB (NFΚB), a proinflammatory transcription factor, is a
commonly observed phenomenon in breast cancer. It facilitates the development of a …

The Notch signaling plays a key role in cell differentiation, survival, and proliferation through
diverse mechanisms. Notch signaling is also involved in vasculogenesis and angiogenesis …

Patients with triple-negative breast cancer display the highest rates of early relapse of all
patients with breast cancer. The basal-like subtype, a subgroup of triple-negative breast …

Self-renewing breast cancer stem cells are key actors in perpetuating tumour existence and
in treatment resistance and relapse. The molecular pathways required for their maintenance …

Extracellular and intracellular mediators of inflammation, such as tumor necrosis factor alpha
(TNFα) and NF‐kappaB (NF‐κB), play major roles in breast cancer pathogenesis …

Significant correlations between obesity and incidence of various cancers have been
reported. Obesity, considered a mild inflammatory process, is characterized by a high level …

Accurate classification of breast tumors is vital for patient management decisions and
enables more precise cancer treatment. Here, we present a quantitative proteotyping …