Time and tide in cerebellar memory formation

CI De Zeeuw, CH Yeo - Current opinion in neurobiology, 2005 - Elsevier
The notion that the olivocerebellar system is crucial for motor learning is well established. In
recent years, it has become evident that there can be many forms of both synaptic and non …

Influence of parallel fiber–Purkinje cell synapse formation on postnatal development of climbing fiber–Purkinje cell synapses in the cerebellum

K Hashimoto, T Yoshida, K Sakimura, M Mishina… - Neuroscience, 2009 - Elsevier
The climbing fiber (CF) to Purkinje cell (PC) synapse in the cerebellum provides an ideal
model for the study of developmental rearrangements of neural circuits. At birth, each PC is …

Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2

ST Hansen, P Meera, TS Otis… - Human molecular …, 2013 - academic.oup.com
Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited
disorder, which is caused by a pathological expansion of a polyglutamine (polyQ) tract in the …

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior

C Nakamoto, M Kawamura, E Nakatsukasa… - PLoS …, 2020 - journals.plos.org
The GluD1 gene is associated with susceptibility for schizophrenia, autism, depression, and
bipolar disorder. However, the function of GluD1 and how it is involved in these conditions …

Gating of neural error signals during motor learning

RR Kimpo, JM Rinaldi, CK Kim, HL Payne… - Elife, 2014 - elifesciences.org
Cerebellar climbing fiber activity encodes performance errors during many motor learning
tasks, but the role of these error signals in learning has been controversial. We compared …

Activity of vestibular nuclei neurons during vestibular and optokinetic stimulation in the alert mouse

M Beraneck, KE Cullen - Journal of neurophysiology, 2007 - journals.physiology.org
As a result of the availability of genetic mutant strains and development of noninvasive eye
movements recording techniques, the mouse stands as a very interesting model for bridging …

Asymmetric recovery in cerebellar-deficient mice following unilateral labyrinthectomy

M Beraneck, JL McKee, M Aleisa… - Journal of …, 2008 - journals.physiology.org
The term “vestibular compensation” refers to the resolution of motor deficits resulting from a
peripheral vestibular lesion. We investigated the role of the cerebellum in the compensation …

Rotational responses of vestibular–nerve afferents innervating the semicircular canals in the C57BL/6 mouse

DM Lasker, GC Han, HJ Park, LB Minor - Journal of the Association for …, 2008 - Springer
Extracellular recordings were made from vestibular–nerve afferents innervating the
semicircular canals in anesthetized C57BL/6 mice ranging in age from 4–24 weeks. A …

The Lurcher mouse: fresh insights from an old mutant

MW Vogel, J Caston, M Yuzaki, J Mariani - Brain research, 2007 - Elsevier
The Lurcher mouse was first discovered in 1954 as a spontaneously occurring autosomal
dominant mutation that caused the degeneration of virtually all cerebellar Purkinje cells and …

The architecture of GluD2 ionotropic delta glutamate receptor elucidated by cryo-EM

AP Burada, R Vinnakota, J Kumar - Journal of Structural Biology, 2020 - Elsevier
GluD2 receptor belongs to the orphan delta family of glutamate receptor ion channels.
These receptors play key roles in synaptogenesis and synaptic plasticity and are associated …