[HTML][HTML] Potent potassium-competitive acid blockers: a new era for the treatment of acid-related diseases

T Oshima, H Miwa - Journal of neurogastroenterology and motility, 2018 - ncbi.nlm.nih.gov
Conventional proton pump inhibitors (PPIs) are used as a first-line therapy to treat acid-
related diseases worldwide. However, they have a number of limitations including slow …

potassium‐competitive acid blockers for the treatment of acid‐related disorders

Y Abdel‐Aziz, DC Metz… - Alimentary Pharmacology …, 2021 - Wiley Online Library
Background Potassium‐competitive acid blockers (P‐CABs) are a novel group of acid‐
suppressing medicines for the management of acid‐related disorders. Aims To review …

Gastroprotection in patients on antiplatelet and/or anticoagulant therapy: a position paper of National Association of Hospital Cardiologists (ANMCO) and the Italian …

MG Abrignani, L Gatta, D Gabrielli, G Milazzo… - European Journal of …, 2021 - Elsevier
Aspirin and P2Y 12 receptor antagonists are widely used across the spectrum of
cardiovascular and cerebrovascular diseases. Gastrointestinal complications, including …

Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study

Y Mizokami, K Oda, N Funao, A Nishimura, S Soen… - Gut, 2018 - gut.bmj.com
Objective To assess the non-inferiority of vonoprazan to lansoprazole for secondary
prevention of non-steroidal anti-inflammatory drug (NSAID)-induced peptic ulcer (PU) and …

Potassium-competitive acid blockers: current clinical use and future developments

C Scarpignato, RH Hunt - Current Gastroenterology Reports, 2024 - Springer
Abstract Purpose of the Review Acid suppression with proton pump inhibitors (PPIs)
represents the standard of care in the treatment of acid-related diseases. However, despite …

Vonoprazan: a novel and potent alternative in the treatment of acid-related diseases

X Yang, Y Li, Y Sun, M Zhang, C Guo, IA Mirza… - Digestive Diseases and …, 2018 - Springer
Although proton pump inhibitors (PPIs) have been used widely, acid-related diseases are
still associated with a huge burden on the health care system. Recently, the efficacy and …

Novel therapies for gastroesophageal reflux disease: beyond proton pump inhibitors

F Shibli, Y Kitayama, R Fass - Current gastroenterology reports, 2020 - Springer
Abstract Purpose of Review Despite the many areas of unmet needs in gastroesophageal
reflux disease (GERD), proton pump inhibitors (PPIs) remain the cornerstone of medical …

[HTML][HTML] Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view

MG Abrignani, A Lombardo, A Braschi… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Aspirin, other antiplatelet agents, and anticoagulant drugs are used across a wide spectrum
of cardiovascular and cerebrovascular diseases. A concomitant proton pump inhibitor (PPI) …

Safety of potassium-competitive acid blockers in the treatment of gastroesophageal reflux disease

A Tietto, S Faggin, C Scarpignato… - Expert Opinion on …, 2025 - Taylor & Francis
ABSTRACT Introduction Proton pump inhibitors (PPIs) are the first-line treatment for
gastroesophageal reflux disease (GERD). However, due to their intrinsic limitations, there …

Acid suppressant therapy: a step forward with potassium-competitive acid blockers

C Scarpignato, RH Hunt - Current Treatment Options in Gastroenterology, 2021 - Springer
Purpose of the review The introduction of H 2-receptor antagonists (H 2 RAs) and proton
pump inhibitors (PPIs) into clinical practice has been a real breakthrough in the treatment of …