Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives

FI Milagro, ML Mansego, C De Miguel… - Molecular aspects of …, 2013 - Elsevier
Nutritional factors play a life-long role in human health. Indeed, there is growing evidence
that one of the mechanisms by which nutrients and bioactive compounds affect metabolic …

DNA methylation in white blood cells: association with risk factors in epidemiologic studies

MB Terry, L Delgado-Cruzata, N Vin-Raviv, HC Wu… - Epigenetics, 2011 - Taylor & Francis
Alterations in DNA methylation patterns, both at specific loci and overall in the genome, have
been associated with many different health outcomes. In cancer and other diseases, most of …

DNA methylation signatures link prenatal famine exposure to growth and metabolism

EW Tobi, JJ Goeman, R Monajemi, H Gu… - Nature …, 2014 - nature.com
Periconceptional diet may persistently influence DNA methylation levels with phenotypic
consequences. However, a comprehensive assessment of the characteristics of prenatal …

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes

AL Teh, H Pan, L Chen, ML Ong, S Dogra… - Genome …, 2014 - genome.cshlp.org
Integrating the genotype with epigenetic marks holds the promise of better understanding
the biology that underlies the complex interactions of inherited and environmental …

Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring

S Finer, C Mathews, R Lowe, M Smart… - Human molecular …, 2015 - academic.oup.com
Exposure of a developing foetus to maternal gestational diabetes (GDM) has been shown to
programme future risk of diabetes and obesity. Epigenetic variation in foetal tissue may have …

Dietary and lifestyle factors of DNA methylation

U Lim, MA Song - Cancer epigenetics: methods and protocols, 2012 - Springer
Lifestyle factors, such as diet, smoking, physical activity, and body weight management, are
known to constitute the majority of cancer causes. Epigenetics has been widely proposed as …

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements

Y Liu, SK Murphy, AP Murtha, BF Fuemmeler… - Epigenetics, 2012 - Taylor & Francis
Depressed mood in pregnancy has been linked to low birth weight (LBW,< 2,500 g), a risk
factor for adult-onset chronic diseases in offspring. We examined maternal depressed mood …

The application of big data to cardiovascular disease: paths to precision medicine

JA Leopold, BA Maron, J Loscalzo - The Journal of clinical …, 2020 - Am Soc Clin Investig
Advanced phenotyping of cardiovascular diseases has evolved with the application of high-
resolution omics screening to populations enrolled in large-scale observational and clinical …

Fetal and infant origins of asthma

L Duijts - European journal of epidemiology, 2012 - Springer
Previous studies have suggested that asthma, like other common diseases, has at least part
of its origin early in life. Low birth weight has been shown to be associated with increased …

In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health

M Argyraki, P Damdimopoulou… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Genomic imprinting is an epigenetic gene regulatory mechanism; disruption
of this process during early embryonic development can have major consequences on both …