The use of human mesenchymal stem cells (hMSCs) in cell-based therapy has attracted
extensive interest in the field of regenerative medicine, and it shows applications to …

The role of adult mesenchymal stem cells (MSC) in tissue maintenance and regeneration
has received significant attention of late. Questions arise to what extent these cells are either …

Senescent cells accumulate in fat with aging. We previously found genetic clearance of
senescent cells from progeroid INK-ATTAC mice prevents lipodystrophy. Here we show that …

BACKGROUND: Mesenchymal stem cells within the stromal-vascular fraction of
subcutaneous adipose tissue, adipose-derived stem cells (ADSCs), produced soluble …

Progenitor cells such as mesenchymal stem cells (MSCs) have elicited great hopes for
therapeutic augmentation of physiological regeneration processes, eg, for bone fracture …

Mesenchymal stem cells (MSCs) possess unique paracrine and immunosuppressive
properties, which make them useful candidates for cellular therapy. Here, we address how …

Cellular senescence is recognized as a critical cellular response to prolonged rounds of
replication and environmental stresses. Its defining characteristics are arrested cell-cycle …

Aging is a time-related process of functional decline at organelle, cellular, tissue, and
organismal level that ultimately limits life. Cellular senescence is a state of permanent …

Mesenchymal stem cells (MSC) which have self-renewal and multiple differentiation
potential in vitro play important roles in regenerative medicine and tissue engineering …

In general terms, the recognized alterations in circulating humoral factors (hormones,
cytokines, growth factors) that occur in ageing, coupled with innate cellular senescence …