[HTML][HTML] Post-translational modifications of the TAK1-TAB complex

Y Hirata, M Takahashi, T Morishita, T Noguchi… - International journal of …, 2017 - mdpi.com
Transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) is a member of the mitogen-
activated protein kinase kinase kinase (MAPKKK) family that is activated by growth factors …

[HTML][HTML] Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling

S Pande, X Yang, R Friesel - Cell Communication and Signaling, 2021 - Springer
Abstract Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar
expression to fibroblast growth factor), is a single pass transmembrane protein that is …

[HTML][HTML] Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions

M Mellett, P Atzei, R Bergin, A Horgan, T Floss… - Nature …, 2015 - nature.com
Receptor families of the innate immune response engage in 'cross-talk'to tailor optimal
immune responses against invading pathogens. However, these responses are subject to …

Paclitaxel induces apoptosis through the TAK1–JNK activation pathway

D Yu‐Wei, Z Li, S Xiong, G Huang, Y Luo… - FEBS Open …, 2020 - Wiley Online Library
Paclitaxel (PTX) has previously been used to treat tumours of various tissue origins, such as
lung, breast, ovarian, prostate cancers and leukemia. PTX‐induced apoptosis is associated …

[HTML][HTML] Interleukin-17 receptor D in physiology, inflammation and cancer

C Girondel, S Meloche - Frontiers in Oncology, 2021 - frontiersin.org
Interleukin-17 receptor D (IL-17RD) is an evolutionarily conserved member of the IL-17
receptor family. Originally identified as a negative regulator of fibroblast growth factor (FGF) …

[HTML][HTML] Regulation of TAK–TAB Complex Activation through Ubiquitylation

J Zhang, L Cao, L Lyu, W Qi, W Yang, R Ren… - Frontiers in Bioscience …, 2024 - imrpress.com
Transforming growth factor-β (TGF-β) activated kinase 1 (TAK1), also named mitogen-
activated protein kinase 7 (MAPK7), forms a pivotal signaling complex with TAK1-binding …

Characterization of Golgi scaffold proteins and their roles in compartmentalizing cell signaling

W Peng, Q Lei, Z Jiang, Z Hu - Journal of molecular histology, 2014 - Springer
Subcellular compartmentalization has become an important theme in cell signaling. In
particular, the Golgi apparatus (GA) plays a prominent role in compartmentalizing signaling …