Ecto-nucleotidases play a pivotal role in purinergic signal transmission. They hydrolyze
extracellular nucleotides and thus can control their availability at purinergic P2 receptors …

Zinc is required for the activity of> 300 enzymes, covering all six classes of enzymes. Zinc
binding sites in proteins are often distorted tetrahedral or trigonal bipyramidal geometry …

We analysed the roles and distribution of metal ions in enzymatic catalysis using available
public databases and our new resource Metal-MACiE (http://www. ebi. ac. uk/thornton …

Calcineurin is a eukaryotic Ca2+-and calmodulin-dependent serine/threonine protein
phosphatase. It is a heterodimeric protein consisting of a catalytic subunit calcineurin A …

In recent years, significant progress has been made in understanding the geometric and
electronic structures of the active sites of non-heme iron enzymes and the contributions of …

Posters and lectures presented at the Seventh International Conference on Bioinorganic
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …

Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

Phytic acid (PA) is the primary storage compound of phosphorus in seeds accounting for up
to 80% of the total seed phosphorus and contributing as much as 1.5% to the seed dry …

Zinc is essential to all forms of life, 1-4 with an average adult human containing ca. 3 g of
zinc. 5 For example, zinc is indispensable for effective growth and development, has …

Metabolic and signaling biochemical pathways have numerous steps that involve the
hydrolytic cleavage of peptide or phosphate ester bonds. Although both types of bonds are …