A rate-limiting step in the prevention and early intervention of depressive disorders in young
people is our insufficient understanding of causal mechanisms. One plausible …

Highlights•Most studies measure morningness/eveningness preference rather than
'chronotype'.•Few longitudinal studies exist, and show contrasting results for the direction of …

Sleep, circadian rhythms, and mental health are reciprocally interlinked. Disruption to the
quality, continuity, and timing of sleep can precipitate or exacerbate psychiatric symptoms in …

Major mood syndromes are among the most common and disabling mental disorders.
However, a lack of clear delineation of their underlying pathophysiological mechanisms is a …

In depression, symptoms range from loss of motivation and energy to suicidal thoughts.
Moreover, in depression alterations might be also observed in the sleep-wake cycle and in …

Sleep and circadian rhythms disturbances (SCRD) in young people at high risk or with early
onset of bipolar disorders (BD) are poorly understood. We systematically searched for …

Objective: Disruptions in biological rhythms and sleep are a core aspect of mood disorders,
with sleep and rhythm changes frequently occurring prior to and during mood episodes …

Background Many patients with bipolar disorder (BD) experience residual symptoms during
their inter-episodic periods. The study aimed to analyse the relationship between residual …

Background Although the disturbance of circadian rhythms represents a significant clinical
feature of major depressive disorder (MDD), the relationship between biological rhythm …

Background Depression and anxiety are topical concerns worldwide, especially among
adolescents. Besides, biological rhythm disorder as a candidate mechanism for mood …