Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: A review
M Bian, Q Ma, Y Wu, H Du… - Journal of enzyme …, 2021 - Taylor & Francis
Inflammation and disease are closely related. Inflammation can induce various diseases,
and diseases can promote inflammatory response, and two possibly induces each other in a …
and diseases can promote inflammatory response, and two possibly induces each other in a …
Mannich bases: Chemical structure, chemistry, coordination bonding and application in aqueous phase corrosion protection
Corrosion remains a significant concern due to its detrimental impact on structures and
equipment's integrity, safety, and performance. The economic and environmental corrosion …
equipment's integrity, safety, and performance. The economic and environmental corrosion …
[HTML][HTML] New Schiff bases derived from dimethylpyridine-1, 2, 4-triazole hybrid as cytotoxic agents targeting gastrointestinal cancers: Design, synthesis, biological …
M Strzelecka, B Wiatrak, P Jawień, Ż Czyżnikowska… - Bioorganic …, 2023 - Elsevier
In this research, a series of novel hybrid structures of dimethylpyridine-1, 2, 4-triazole Schiff
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …
Novel Mannich bases derived from 1, 2, 4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations
The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw …
M Szandruk-Bender, A Merwid-Ląd… - Journal of …, 2021 - Taylor & Francis
Background and Purpose Due to the risk of gastrointestinal damage and various tissue
toxicity associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, investigating …
toxicity associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, investigating …
Design and synthesis of coumarin-triazole hybrids: biocompatible anti-diabetic agents, in silico molecular docking and ADME screening
The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (ae) in four
steps starting from substituted salicylaldehyde 1 (ae), and diethyl malonate 2. The …
steps starting from substituted salicylaldehyde 1 (ae), and diethyl malonate 2. The …
Design and synthesis of novel dithiazole carboxylic acid Derivatives: In vivo and in silico investigation of their Anti-Inflammatory and analgesic effects
Inflammation is a complex set of interactions that can occur in tissues as the body's
defensive response to infections, trauma, allergens, or toxic compounds. Therefore, in …
defensive response to infections, trauma, allergens, or toxic compounds. Therefore, in …
Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4,5-Dihydro-1H-1,2,4-triazol-5-one derivatives; an in vitro and in silico study
In this study, a series of novel Schiff bases (4a-4h) containing 1, 2, 4-triazole structure were
synthesized through a condensation reaction of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2 …
synthesized through a condensation reaction of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2 …
New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity—Design, Synthesis and Complementary In Vitro …
Ł Szczukowski, E Krzyżak, B Wiatrak, P Jawień… - International Journal of …, 2021 - mdpi.com
Regarding that the chronic use of commonly available non-steroidal and anti-inflammatory
drugs (NSAIDs) is often restricted by their adverse effects, there is still a current need to …
drugs (NSAIDs) is often restricted by their adverse effects, there is still a current need to …
Recent developments in the chemistry of 1H-and 4H-1, 2, 4-triazoles
Abstract 1H-and 4H-1, 2, 4-Triazoles have wide potent biological applications; therefore,
developing new synthetic routes for such interesting scaffolds is of great importance. The …
developing new synthetic routes for such interesting scaffolds is of great importance. The …