Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening
conditions. Thanks to advancements in vaccine development, vaccines are now available …

The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with
the classical hypothesis-driven laboratory-based analysis of microbes to identify …

The complement system is an essential player in innate and adaptive immunity. It consists of
three pathways (alternative, classical, and lectin) that initiate either spontaneously …

Infections with Neisseria meningitidis and Neisseria gonorrhoeae have different clinical
manifestations, but the bacteria share up to 80–90% genome sequence identity. The …

Introduction: Neisseria meningitidis serogroup B (MenB) is the most common cause of
bacterial meningitis in many industrialized countries and occurs at any age. The highest …

The human complement system plays an important role in the defense against invading
pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly …

Abstract Background The Meningococcal Antigen Typing System (MATS) was developed to
identify meningococcus group B strains with a high likelihood of being covered by the …

Neisseria meningitidis (Nm) clonal complex 11 (cc11) lineage is a hypervirulent pathogen
responsible for outbreaks of invasive meningococcal disease, including among men who …

As microbial genomics makes increasingly important contributions to clinical and public
health microbiology, the interpretation of whole-genome sequence data by nonspecialists …

Mass spectrometry‐based proteomics has been extensively used to map bacterial
proteomes, which has led to a better understanding of the molecular mechanisms …