Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

In this study, we researched the reactions of 5-(5-bromofuran-2-yl)-4-methyl-1, 2, 4-triazole-3-
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …

The wide biological actions of triazolotriazine hybrids, benzene‐sulfonamide derivatives,
exhibit a good chance of displaying in vitro anti‐inflammatory effects. An operationally …

Substituted-1, 2, 4-triazole-5-thiones are versatile synthetic intermediates for the preparation
of several biologically active N-bridged heterocyclic compounds, given that they have two …

A total of 52 novel 1, 2, 4-triazole thioether and thiazolo [3, 2-b]-1, 2, 4-triazole derivatives
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …

The Trimethoxyphenyl (TMP) group serves as a pharmacophore in numerous potent agents
exhibiting diverse bioactivity effects. This moiety is prominently present in the molecular …

Abstract A new series of 1, 2, 4-triazole-5-thione Mannich derivatives containing a naproxen
moiety (1a-o) was designed and synthesized to create naproxen analogs, with the aim of …

Newly designed triazolothiadiazines incorporating with structural motifs of nonsteroidal
analgesic anti-inflammatory drugs were synthesized and screened for their bioactivity …

As a part of our ongoing studies in developing new derivatives as antimicrobial agents we
describe the synthesis of novel substituted 5-benzylideno-2-adamantylthiazol [3, 2-b][1, 2, 4] …

Abstract A series of pyridin-3/4-yl-thiazolo [3, 2-b][1, 2, 4] triazole derivatives (5a–g, 6a–g)
were synthesised by Hantzsch condensation of 5-pyridin-3/4-yl-1, 2, 4-triazole-3-thiol and …